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Third National Health and Nutrition Examination Survey
(NHANES III), 1988-94
Catalog Number 76300
NHANES III LABORATORY DATA FILE DOCUMENTATION
Ages one year and older
December 1996
Table of Contents
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Guidelines for Data Users. . . . . . . . . . . . . . . . . . . . . . . .
Survey Description . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sample Design and Analysis Guidelines. . . . . . . . . . . . . . . . . .
Data Preparation and Processing Procedures . . . . . . . . . . . . . . .
General References . . . . . . . . . . . . . . . . . . . . . . . . . . .
NHANES III Laboratory Data
General Information . . . . . . . . . . . . . . . . . . . . . . . .
Data File Index . . . . . . . . . . . . . . . . . . . . . . . . . .
Data File Item Descriptions, Codes, Counts, and Notes . . . . . . .
References . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Introduction
The National Center for Health Statistics (NCHS) of the Centers for Disease
Control and Prevention (CDC) collects, analyzes, and disseminates data on
the health status of U.S. residents. The results of surveys, analyses, and
studies are made known through a number of data release mechanisms
including publications, mainframe computer data files, CD-ROMs (Search and
Retrieval Software, Statistical Export and Tabulation System (SETS)), and the
Internet (http://www.cdc.gov/nchswww/nchshome.htm).
The National Health and Nutrition Examination Survey (NHANES) is a periodic
survey conducted by NCHS. The third National Health and Nutrition
Examination Survey (NHANES III), conducted from 1988 through 1994, was the
seventh in a series of these surveys based on a complex, multi-stage sample
plan. It was designed to provide national estimates of the health and
nutritional status of the United States' civilian, noninstitutionalized
population aged two months and older.
Data from NHANES III are being released in five public release data files:
NHANES III Household Adult Data File (Catalog Number 77560)
NHANES III Household Youth Data File (Catalog Number 77550)
NHANES III Examination Data File (Catalog Number 76200)
NHANES III Laboratory Data File (Catalog Number 76300)
NHANES III Dietary Recall Data Files (Catalog Number 76700)
A table showing the location of the interview and examination components in
the five NHANES III public release data files follows.
Location of the interview and examination components in the five NHANES III
public release data files
Data File
Topic | HA | HY | EXAM | LAB | DIET |
-----------------------------------------+-----+-----+-------+-----+------+
Sample weights | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Age/race/sex | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Ethnic background | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Household composition | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Individual characteristics | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Health insurance | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Family background | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Occupation of family head | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Housing characteristics | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Family characteristics | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Orientation | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Health services | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Selected health conditions | X | X | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Diabetes questions | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
High blood pressure and | X | . | . | . | . |
cholesterol questions | | | | | |
-----------------------------------------+-----+-----+-------+-----+------+
Cardiovascular disease questions | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Musculoskeletal conditions | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Physical functioning questions | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Gallbladder disease questions | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Location of the interview and examination components in the five NHANES III
public release data files (continued)
Data File
Topic | HA | HY | EXAM | LAB | DIET |
-----------------------------------------+-----+-----+-------+-----+------+
Kidney conditions | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Respiratory and allergy questions | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Diet questions | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Food frequency | X | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Vision questions | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Hearing questions | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Dental care and status | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Tobacco | X | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Occupation | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Language usage | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Exercise | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Social support/residence | X | . | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Vitamin/mineral/medicine usage | X | X | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Blood pressure measurement | X | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Birth | . | X | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Infant feeding practices/diet | . | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Motor and social development | . | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Functional impairment | X | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
School attendance | . | X | . | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Cognitive function | . | X | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Location of the interview and examination components in the five NHANES III
public release data files (continued)
Data File
Topic | HA | HY | EXAM | LAB | DIET |
-----------------------------------------+-----+-----+-------+-----+------+
Alcohol and drug use | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Reproductive health | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Diagnostic interview schedule | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Activity | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Physician's examination | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Height and weight | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Body measurements | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Dental examination | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Allergy skin test | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Audiometry | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Tympanometry | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
WISC and WRAT | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Spirometry | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Bone densitometry | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Gallbladder ultrasonography | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Central nervous system | . | . | X | . | . |
function evaluation | | | | | |
-----------------------------------------+-----+-----+-------+-----+------+
Fundus photography | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Physical function evaluation | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Fasting questions | . | . | . | X | . |
-----------------------------------------+-----+-----+-------+-----+------+
Location of the interview and examination components in the five NHANES III
public release data files (continued)
Data File
Topic | HA | HY | EXAM | LAB | DIET |
-----------------------------------------+-----+-----+-------+-----+------+
Laboratory tests on blood and urine | . | . | . | X | . |
-----------------------------------------+-----+-----+-------+-----+------+
Total nutrient intakes | . | . | X | . | . |
-----------------------------------------+-----+-----+-------+-----+------+
Individual foods | . | . | . | . | X |
-----------------------------------------+-----+-----+-------+-----+------+
Combination foods | . | . | . | . | X |
-----------------------------------------+-----+-----+-------+-----+------+
Ingredients | . | . | . | . | X |
-----------------------------------------+-----+-----+-------+-----+------+
Data File Definitions
HA - Household Adult Data File
HY - Household Youth Data File
EXAM - Examination Data File
LAB - Laboratory Data File
DIET - Dietary Recall Data Files
This document includes the documentation for the NHANES III Laboratory Data
File and also contains a general overview of the survey and the use of the
data files. The general overview includes five sections. The first
section, entitled "Guidelines for Data Users," contains important information
about the use of the data files. The second section, "Survey Description,"
is a brief overview of the survey plan and operation. The third section,
"Sample Design and Analysis Guidelines," describes some technical aspects of
the sampling plan and discusses some analytic issues particularly related to
the use of data from complex sample surveys. The "Data Preparation and
Processing Procedures" section describes the editing conventions and the
codes used to represent the data. The last and fifth section, "General
References," includes a reference list for the survey overview sections of
the document.
Public Use Data Files for the third National Health and Nutrition
Examination Survey will also be available from the National Technical
Information Service (NTIS). A list of NCHS public use data tapes available
for purchase from NTIS may be obtained from the Data Dissemination Branch at
NCHS. Information regarding a bibliography (on disk) of journal articles
citing data from all the NHANES and the availability of NHANES III data in
CD-ROM/SETS software format can be obtained from the Data Dissemination
Branch(301-436-8500) or by writing to:
Data Dissemination Branch
National Center for Health Statistics
Room 1018
6525 Belcrest Road
Hyattsville, Maryland 20782
NTIS can be contacted at:
NTIS - Computer Products Office
5285 Port Royal Road
Springfield, Virginia 22161
(703) 487-4807
Copies of all NHANES III questionnaires and data collection forms are
included in the Plan and Operation of the Third National Health and
Nutrition Examination Survey, 1988-94 (NCHS, 1994; U.S. DHHS, 1996). This
publication, along with detailed information on NHANES procedures,
interviewing, data collection, quality control techniques, survey design,
nonresponse, and sample weighting can be found on the NHANES III Reference
Manuals and Reports CD-ROM (U.S. DHHS, 1996). Information on how to order
this CD-ROM is available from the Data Dissemination Branch at NCHS at the
address and telephone number given above.
GUIDELINES FOR DATA USERS
Please refer to the following important information before analyzing data.
NHANES III Background Documents
o The Plan and Operation of the Third National Health and Nutrition
Examination Survey, 1988-94, (NCHS, 1994; U.S. DHHS, 1996) provides an
overview of the survey and includes copies of the survey forms.
o The sample design, nonresponse, and analytic guidelines documents on
the NHANES III Reference Manuals and Reports CD-ROM (U.S. DHHS, 1996)
discuss the reasons that sample weights and the complex survey design
should be taken into account when conducting any analysis.
o Instruction manuals, laboratory procedures, and other NHANES III
reference manuals on the NHANES III Reference Manuals and Reports
CD-ROM(U.S. DHHS, 1996) are also available for further information on
the details of the survey.
Analytic Data Set Preparation
o Most NHANES III survey design and demographic variables are found only
on the Adult and Youth Household Data Files. In preparing a data set
for analysis, other data files must be merged with either or both of
these files to obtain many important analytic variables.
o All of the NHANES III public use data files are linked with the common
survey participant identification number (SEQN). Merging information
from multiple NHANES III data files using this variable ensures that
the appropriate information for each survey participant is linked
correctly.
o NHANES III public use data files do not have the same number of
records on each file. The Household Questionnaire Files (divided into
two files, Adult and Youth) contain more records than the Examination
Data File because not everyone who was interviewed completed the
examination. The Laboratory Data File contains data only for persons
aged one year and older. The Individual Foods Data File based on the
dietary recall has multiple records for each person rather than the one
record per sample person contained in the other data files.
o For each data file, SAS program code with standard variable names and
labels is provided as separate text files on the CD-ROM that contains
the data files. This SAS program code can be used to create a SAS
data set from the data file.
o Modifications were made to items in the questionnaires, laboratory,
and examination components over the course of the survey; as a result,
data may not be available for certain variables for the full six years.
In addition, variables may differ by phase since some changes were
implemented between phases. Users are encouraged to read the Notes
sections of this document carefully for information about changes.
o Extremely high and low values have been verified whenever possible,
and numerous consistency checks have been performed. Nonetheless, users
should examine the range and frequency of values before analyzing
data.
o Some data were not ready for release at the time of this publication
due to continued processing of the data or analysis of laboratory
specimens. A listing of those data are available in the general
information section of each data file.
o Confidential and administrative data are not being released to the
public. Additionally, some variables have been recoded to help
protect the confidentiality of the survey participants. For example,
all age-related variables were recoded to 90+ years for persons who were
90 years of age and older.
o Some variable names may differ from those used in the Phase 1 NHANES
III Provisional Data Release and some variables included in the Phase 1
provisional release may not appear on these files.
o Although the data files have been edited carefully, errors may be
detected. Please notify NCHS staff (301-436-8500) of any errors in
the data file or the documentation.
Analytic Considerations
o NHANES III (1988-94) was designed so that the survey's first three
years, 1988-91, its last three years, 1991-94, and the entire six
years were national probability samples. Analysts are encouraged to use
all six years of survey results.
o Sample weights are available for analyzing NHANES III data. One of
the following three sample weights will be appropriate for nearly all
analyses: interviewed sample final weight (WTPFQX6), examined sample
final weight (WTPFEX6), and mobile examination center (MEC)- and
home-examined sample final weight (WTPFHX6). Choosing which of these
sample weights to use in any analysis depends on the variables being
used. A good rule of thumb is to use "the least common denominator"
approach. In this approach, the user checks the variables of
interest. The variable that was collected on the smallest number of
persons is the "least common denominator," and the sample weight that
applies to that variable is the appropriate one to use for that
analysis. For more detailed information, see the Analytic and Reporting
Guidelines for NHANES III (U.S. DHHS, 1996).
Referencing or Citing NHANES III Data
o In publications, please acknowledge NCHS as the original data source.
For instance, the reference for the NHANES III Laboratory Data File
is:
U.S. Department of Health and Human Services (DHHS). National Center
for Health Statistics. Third National Health and Nutrition
Examination Survey, 1988-1994, NHANES III Laboratory Data File (CD-ROM).
Public Use Data File Documentation Number 76200. Hyattsville, MD.:
Centers for Disease Control and Prevention, 1996. Available from
National Technical Information Service (NTIS), Springfield, VA.
Acrobat. PDF format; includes access software: Adobe Systems, Inc.
Acrobat Reader 2.1.
o Please place the acronym "NHANES III" in the titles or abstracts of
journal articles and other publications in order to facilitate the
retrieval of such materials in bibliographic searches.
SURVEY DESCRIPTION
The third National Health and Nutrition Examination Survey (NHANES III) was
the seventh in a series of large health examination surveys conducted in
the United States beginning in 1960. Three of these surveys, the National
Health Examination Surveys (NHES), were conducted in the 1960's (NCHS, 1965;
NCHS, 1967; NCHS, 1969). In 1970, an expanded nutrition component was added
to provide data with which to assess nutritional status and dietary
practices, and the name was changed to the National Health and Nutrition
Examination Survey (Miller, 1973; Engel, 1978; McDowell, 1981). A special
survey of Hispanic populations in the United States was conducted during
1982-1984 (NCHS, 1985).
The general structure of the NHANES III sample design was similar to that
of the previous NHANES. All of the surveys used complex, multi-stage,
stratified, clustered samples of civilian, noninstitutionalized
populations. NHANES III was the first NHANES without an upper age limit; in
fact, the age range for the survey was two months and older. A home
examination option was employed for the first time in order to obtain
examination data for very young children and for elderly persons who were
unable to visit the mobile examination center (MEC). The home examination
included only a subset of the components used in the full MEC examination
since it would have been difficult to collect some types of data in a home
setting. A detailed description of design specifications and copies of the
data collection forms can be found in the Plan and Operation of the Third
National Health and Nutrition Examination Survey, 1988-1994 (NCHS, 1994; U.S.
DHHS, 1996).
NHANES III was conducted from October 1988 through October 1994 in two
phases, each of which comprised a national probability sample. The first
phase was conducted from October 18, 1988, through October 24, 1991, at 44
locations. The second phase was conducted from September 20, 1991, through
October 15, 1994, at 45 different locations. In NHANES III, 39,695 persons
were selected over the six years; of those, 33,994 (86%) were interviewed
in their homes. All interviewed persons were invited to the MEC for a
medical examination. Seventy-eight percent (30,818) of the selected persons
were examined in the MEC, and an additional 493 persons were given a special,
limited examination in their homes.
Data collection began with a household interview. Several questionnaires
were administered in the household: Household Screener Questionnaire,
Family Questionnaire, Household Adult Questionnaire, and Household Youth
Questionnaire.
At the MEC, an examination was performed, and five automated questionnaires
or interviews were administered: MEC Adult Questionnaire, MEC Youth
Questionnaire, MEC Proxy Questionnaire, 24-Hour Dietary Recall, and Dietary
Food Frequency (ages 12-16 years). The health examination component
included a variety of tests and procedures. The examinee's age at the time
of the interview and other factors determined which procedures were
administered. Blood and urine specimens were obtained, and a number of tests
and measurements were performed including body measurements, spirometry,
fundus photography, x-rays, electrocardiography, allergy and glucose
tolerance tests, and ultrasonography. Measurements were taken of bone
density, hearing, and physical, cognitive, and central nervous system
functions. A physician performed a limited standardized medical examination
and a dentist performed a standardized dental examination. While some of the
blood and urine analyses were performed in the MEC laboratory, most analyses
were conducted elsewhere by contract laboratories.
A home examination was conducted for those sample persons aged 2-11 months
and aged 20 years or older who were unable to visit the mobile examination
center. The home examination consisted of an abbreviated version of the
tests and interviews performed in the MEC. Depending on age of the sample
person, the components included body measurements, blood pressure,
spirometry, venipuncture, physical function evaluation, and a questionnaire
to inquire about infant feeding, selected health conditions, cognitive
function, tobacco use, and reproductive history.
SAMPLE DESIGN AND ANALYSIS GUIDELINES
Sample Design
The general structure of the NHANES III sample design is the same as that
of the previous NHANES. Each of these surveys used a stratified, multi-stage
probability design. The major design parameters of the two previous NHANES
and the special Hispanic HANES, as well as NHANES III, have been previously
summarized (Miller, 1973; McDowell, 1981; NCHS, 1985; NCHS, 1994). The
NHANES III sample was designed to be self-weighting within a primary
sampling unit (PSU) for subdomains (age, sex, and race-ethnic groups). While
the sample was fairly close to self-weighting nationally for each of these
subdomain groups, it was not representative of the total population, which
includes institutionalized, non-civilian persons that were outside the
scope of the survey.
The NHANES III sample represented the total civilian, noninstitutionalized
population, two months of age or over, in the 50 states and the District of
Columbia of the United States. The first stage of the design consisted of
selecting a sample of 81 PSU's that were mostly individual counties. In a
few cases, adjacent counties were combined to keep PSU's above a minimum
population size. The PSU's were stratified and selected with probability
proportional to size (PPS). Thirteen large counties (strata) were chosen
with certainty (probability of one). For operational reasons, these 13
certainty PSU's were divided into 21 survey locations. After the 13
certainty strata were designated, the remaining PSU's in the United States
were grouped into 34 strata, and two PSU's were selected per stratum (68
survey locations). The selection was done with PPS and without
replacement. The NHANES III sample therefore consists of 81 PSU's or 89
locations.
The 89 locations were randomly divided into two groups, one for each phase.
The first group consisted of 44 and the other of 45 locations. One set
of PSU's was allocated to the first three-year survey period (1988-91) and
the other set to the second three-year period (1991-94). Therefore,
unbiased estimates (from the point of view of sample selection) of health and
nutrition characteristics can be independently produced for both Phase 1
and Phase 2 as well as for both phases combined.
For most of the sample, the second stage of the design consisted of area
segments composed of city or suburban blocks, combinations of blocks, or
other area segments in places where block statistics were not produced in
the 1980 Census. In the first phase of NHANES III, the area segments were
used only for a sample of persons who lived in housing units built before
1980. For units built in 1980 and later, the second stage consisted of sets
of addresses selected from building permits issued in 1980 or later. These
are referred to as "new construction segments." In the second phase, 1990
Census data and maps were used to define the area segments. Because the
second phase followed within a few years of the 1990 Census, new construction
did not account for a significant part of the sample, and the entire sample
came from the area segments.
The third stage of sample selection consisted of households and certain
types of group quarters, such as dormitories. All households and eligible
group quarters in the sample segments were listed, and a subsample was
designated for screening to identify potential sample persons. The
subsampling rates enabled production of a national, approximately
equal-probability sample of households in most of the United States with
higher rates for the geographic strata with high Mexican-American
populations. Within each geographic stratum, there was a nearly
equal-probability sample of households across all 89 stands.
Persons within the sample of households or group quarters were the fourth
stage of sample selection. All eligible members within a household were
listed, and a subsample of individuals was selected based on sex, age, and
race or ethnicity. The definitions of the sex, age, race or ethnic
classes, subsampling rates, and designation of potential sample persons
within screened households were developed to provide approximately
self-weighting samples for each subdomain within geographic strata and at the
same time to maximize the average number of sample persons per sample
household. Previous NHANES indicated that this increased the overall
participation rate. Although the exact sample sizes were not known until
data collection was completed, estimates were made. Below is a summary of
the sample sizes for the full six-year NHANES III at each stage of selection:
Number of PSU's 81
Number of stands (survey locations) 89
Number of segments 2,144
Number of households screened 93,653
Number of households with sample persons 19,528
Number of designated sample persons 39,695
Number of interviewed sample persons 33,994
Number of MEC-examined sample persons 30,818
Number of home-examined sample persons 493
More detailed information on the sample design and weighting and estimation
procedures for NHANES III can be found in the Plan and Operation of the
Third National Health and Nutrition Examination Survey, 1988-94 (NCHS, 1994;
U.S. DHHS, 1996) and in the Analytic and Reporting Guidelines: Third National
Health and Nutrition Examination Survey (NHANES III), 1988-94 (U.S. DHHS,
1996).
Analysis Guidelines
Because of the complex survey design used in NHANES III, traditional
methods of statistical analysis based on the assumption of a simple random
sample are not applicable. Detailed descriptions of this issue and possible
analytic methods for analyzing NHANES data have been described earlier (NCHS,
1985; Yetley, 1987; Landis, 1982; Delgado, 1990). Recent analytic and
reporting guidelines that should be used for most NHANES III analyses and
publications are contained in Analytic and Reporting Guidelines (U.S. DHHS,
1996). These recommendations differ slightly from those used by analysts for
previous NHANES surveys. These suggested guidelines provide a framework to
users for producing estimates that conform to the analytic design of the
survey. All users are strongly urged to review these analytic and reporting
guidelines before beginning any analyses of NHANES III data.
It is important to remember that this set of statistical guidelines is not
absolute. When conducting analyses, the analyst needs to use his/her
subject matter knowledge (including methodological issues) as well as
information about the survey design. The more one deviates from the original
analytic categories defined in the sample design, the more important it is to
evaluate the results carefully and to interpret the findings cautiously.
In NHANES III, 89 survey locations were randomly divided into two sets or
phases, the first consisting of 44 and the other of 45 locations. One set
of PSU's was allocated to the first three-year survey period (1988-91) and
the other set to the second three-year period (1991-94). Therefore, unbiased
national estimates of health and nutrition characteristics can be
independently produced for each phase as well as for both phases combined.
Computation of national estimates from both phases combined (i.e., total
NHANES III) is the preferred option; individual phase estimates may be
highly variable. In addition, individual phase estimates are not
statistically independent. It is also difficult to evaluate whether
differences in individual phase estimates are real or due to methodological
differences. That is, differences may be due to changes in sampling methods
or data collection methodology over time. At this time, there is no valid
statistical test for examining differences between Phase 1 and Phase 2.
Therefore, although point estimates can be produced separately for each
phase, no test is available to test whether those estimates are
significantly different from each other.
NHANES III is based on a complex, multi-stage probability sample design.
Several aspects of the NHANES design must be taken into account in data
analysis, including the sample weights and the complex survey design.
Appropriate sample weights are needed to estimate prevalence, means,
medians, and other statistics. Sample weights are used to produce correct
population estimates because each sample person does not have the same
probability of selection. The sample weights incorporate the differential
probabilities of selection and include adjustments for noncoverage and
nonresponse. A detailed discussion of nonresponse adjustments and issues
related to survey coverage have been published (U.S. DHHS, 1996). With the
large oversampling of young children, older persons, black persons, and
Mexican-Americans in NHANES III, it is essential that the sample weights be
used in all analyses. Otherwise, a misinterpretation of results is highly
likely. Other aspects of the design that must be taken into account in data
analyses are the strata and PSU pairings from the sample design. These
pairings should be used to estimate variances and test for statistical
significance. For weighted analyses, analysts can use special computer
software packages that use an appropriate method for estimating variances for
complex samples such as SUDAAN (Shah, 1995) and WesVarPC (Westat, 1996).
Although initial exploratory analyses may be performed on unweighted data
using standard statistical packages and assuming simple random sampling,
final analyses should be done on weighted data using appropriate sample
weights. A summary of the weighting methodology and the type of sample
weights developed for NHANES III is included in Weighting and Estimation
Methodology (U.S. DHHS, 1996).
The purpose of weighting the sample data is to permit analysts to produce
estimates of statistics that would have been obtained if the entire
sampling frame (the United States) had been surveyed. Sample weights can be
considered as measures of the number of persons the particular sample
observation represents. Weighting takes into account several features of
the survey: the specific probabilities of selection for the individual
domains that were oversampled as well as nonresponse and differences between
the sample and the total U.S. population. Differences between the sample and
the population may arise due to sampling variability, differential
undercoverage in the survey among demographic groups, and possibly other
types of response errors, such as differential response rates or
misclassification errors. Sample weighting in NHANES III was used to:
1. Compensate for differential probabilities of selection among subgroups
(i.e., age-sex-race-ethnicity subdomains where persons living in
different geographic strata were sampled at different rates);
2. Reduce biases arising from the fact that nonrespondents may be
different from those who participate;
3. Bring sample data up to the dimensions of the target population
totals;
4. Compensate, to the extent possible, for inadequacies in the sampling
frame (resulting from omissions of some housing units in the listing
of area segments, omissions of persons with no fixed address, etc.); and
5. To reduce variances in the estimation procedure by using auxiliary
information that is known with a high degree of accuracy.
In NHANES III, the sample weighting was carried out in three stages. The
first stage involved the computation of weights to compensate for unequal
probabilities of selection (objective 1, above). The second stage adjusted
for nonresponse (objective 2). The third stage used poststratification of
the sample weights to Census Bureau estimates of the U.S. population to
accomplish the third, fourth, and fifth objectives simultaneously. In
NHANES III, several types of sample weights (see the sample weights table
that follows) were computed for the interviewed and examined sample and are
included in the NHANES III data file. Also, sample weights were computed
separately for Phase 1 (1988-91), Phase 2 (1991-94), and total NHANES III
(1988-94) to facilitate analysis of items collected only in Phase 1, only
in Phase 2, and over six years of the survey. Three sets of pseudo strata
and PSU pairings are provided to use with SUDAAN in variance estimation.
Since NHANES III is based on a complex, multi-stage sample design,
appropriate sample weights should be used in analyses to produce national
estimates of prevalence and associated variances while accounting for
unequal probability of selection of sample persons. For example, the final
interview weight, WTPFQX6, should be used for analysis of the items or
questions from the family or household questionnaires, and the final MEC
examination weight, WTPFEX6, should be used for analysis of the
questionnaires and measurements administered in the MEC. Furthermore, for a
combined analysis of measurements from the MEC examinations and associated
medical history questions from the household interview, the final MEC
examination weight, WTPFEX6, should be used. We recommend using SUDAAN
(Shah, 1995) to estimate statistics of interest and the associated variance.
However, one can also use other published methods for variance estimation.
Application of SUDAAN and alternative methods, such as the average design
effect approach, balance repeated replication (BRR) methods, or jackknife
methods for variance estimation, are discussed in Weighting and Estimation
Methodology (U.S. DHHS, 1996).
Appropriate Uses of the NHANES III Sample Weights
Final interview weight, WTPFQX6
Use only in conjunction with the sample interviewed at home and
with items collected during the household interview.
Final examination (MEC only) weight, WTPFEX6
Use only in conjunction with the MEC-examined sample and with
interview and examination items collected at the MEC.
Final MEC+home examination weight, WTPFHX6
Use only in conjunction with the MEC+home-examined sample and
with items collected at both the MEC and home.
Final allergy weight, WTPFALG6
Use only in conjunction with the allergy subsample and with items
collected as part of the allergy component of the exam.
Final CNS weight, WTPFCNS6
Use only in conjunction with the CNS subsample and with items
collected as part of the CNS component of the exam.
Final morning examination (MEC only) subsample weight, WTPFSD6
Use only in conjunction with the MEC-examined persons assigned to
the morning subsample and only with items collected in the MEC
exam.
Final afternoon/evening examination (MEC only) subsample weight, WTPFMD6
Use only in conjunction with the MEC-examined persons assigned to
the afternoon/evening subsample and only with items collected in
the MEC exam.
Final morning examination (MEC+home) subsample weight, WTPFHSD6
Use only in conjunction with the MEC- and home-examined persons
assigned to the morning subsample and with items collected during
the MEC and home examinations.
Final afternoon/evening examination (MEC+home) weight, WTPFHMD6
Use only in conjunction with the MEC- and home-examined persons
assigned to the afternoon/evening subsample and with items
collected during the MEC and home examinations.
DATA PREPARATION AND PROCESSING PROCEDURES
Automated data collection procedures for the survey were introduced in
NHANES III. In the mobile examination centers, data for the interview and
examination components were recorded directly onto a computerized data
collection form. With the exception of a few independently automated
systems, the system was centrally integrated. This operation allowed for
ongoing monitoring of much of the data. Before the introduction of the
computer-assisted personal interview (CAPI), the household questionnaire
data were reviewed manually by field editors and interviewers. CAPI
(1992-1994 only) questionnaires featured built-in edits to prevent entering
inconsistencies and out-of-range responses. The multi-level data
collection and quality control systems are discussed in detail in the Plan
and Operation of the Third National Health and Nutrition Examination Survey,
1988-1994 (NCHS, 1994; U.S. DHHS, 1996). All interview, laboratory, and
examination data were sent to NCHS for final processing.
Guidelines were developed that provided standards for naming variables,
filling missing values and coding conventional responses, handling missing
records, and standardizing two-part quantity/unit questionnaire variables.
NCHS staff, assisted by contract staff, developed data editing
specifications that checked data sets for valid codes, ranges, and skip
pattern consistencies and examined the consistency of values between
interrelated variables. Comments, collected in both interviews and
examination components, were reviewed and recoded when possible. Responses
to "Other" and "Specify" were recoded either to existing code categories or
to new categories. The documentation for each data set includes notes for
those variables that have been recoded and standardized and for those
variables that differ significantly from what appears in the original data
collection instrument. While the data have undergone many quality control
and editing procedures, there still may be values that appear extreme or
illogical. Values that varied considerably from what was expected were
examined by analysts who checked for comments or other responses that might
help to clarify unusual values. Generally, values were retained unless they
could not possibly be true, in which case they were changed to "Blank but
applicable." Therefore, the user must review each data set for extreme or
inconsistent values and determine the status of each value for analysis.
Several editing conventions were used in the creation of final analytic
data sets:
1. Standardized variables were created to replace all two-part
quantity/unit questions using standard conversion factors.
Standardized variables have the same name as the variable of the
two-part question with an "S" suffix. For instance, MAPF18S (Months
received WIC benefits) in the MEC Adult Questionnaire was created from
the two-part response option to question F18, "How long did you receive
benefits from the WIC program?," using the conversion factor 12 months
per year.
2. Recoded variables were created by combining responses from two or more
like variables, or by collapsing responses to create a summary
variable for the purpose of confidentiality. Recoded variables have the
original variable name with an R suffix. For example, place of birth
variable (HFA6X) in the Family Questionnaire was collapsed to a three
level response category (U.S., Mexico, Other) and renamed HFA6XR.
Generally, only the recoded variable has been included in the data file.
3. Fill values, a series of one or more digits, were used to represent
certain specific conditions or responses. Below is a list of the fill
values that were employed. Some of the fill values pertain only to
questionnaire data, although 8-fill and blank-fill values are found in
all data sets. Other fill values, not included in this list, are used
to represent component-specific conditions.
6-fills = Varies/varied. (Questionnaires only)
7-fills = Fewer than the smallest number that could be reported within
the question structure (e.g., fewer than one cigarette per day).
(Questionnaires only)
8-fills = Blank but applicable/cannot be determined. This means that
a respondent was eligible to receive the question, test, or component
but did not because of refusal, lack of time, lack of staff, loss of
data, broken vial, language barrier, unreliability, or other similar
reasons.
9-fills = Don't know. This fill was used only when a respondent did
not know the response to a question and said, "I don't know."
(Questionnaires only)
Blank fills = Inapplicable. If a respondent was not eligible for a
questionnaire, test, or component because of age, gender, or specific
reason, the variable was blank-filled. In the questionnaire, if a
respondent was not asked a question because of a skip-pattern,
variables corresponding to the question were blank-filled. For
examination or laboratory components, if a person was excluded by a
defined protocol (e.g., screening exclusion questions) and these
criteria are included in the data set, then the corresponding
variables were blank-filled for that person. For home examinees,
variables for examination components and blood tests not performed as
part of the home examination protocol were blank-filled.
4. For variables describing discrete data, codes of zero (0) were used to
mean "none," "never," or the equivalent. Value labels for which "0"
is used include: "has not had," "never regularly," "still taking," or
"never stopped using." Unless otherwise labeled, for variables
containing continuous data, "zero" means "zero.
5. Where there are logical skip patterns in the flow of the questionnaire
or examination component, the skip was indicated by placing the
variable label of the skip destination in parentheses as part of the
value label of the response generating the skip. For example, in the
Physical Function Evaluation, the variable PFPWC (in wheelchair) has a
value label, "2 No (PFPSCOOT)" that means that the next item for
persons not in a wheelchair would be represented by the variable,
PFPSCOOT.
Variable Nomenclature
A unique name was assigned to every NHANES III variable using a standard
convention. By following this naming convention, the origin of each
variable is clear, and there is no chance of overlaying similar variables
across multiple components. Variables range in length from three to eight
characters. The first two variable characters represent the topic (e.g.,
analyte, questionnaire instrument, examination component) and are listed
below alphabetically by topic. For questionnaires administered in the
household, the remainder of the variable name following the first two
characters indicates the question section and number. For example, data
for the response to the Household Adult Questionnaire question B1 are
contained in the variable HAB1. For most laboratory and examination
variables, as well as some other variables, a "P" in the third position
refers to "primary" and the remainder of the variable name is a brief
description of the item. For instance, in the Laboratory Data File,
information on the length of time the person fasted before the first blood
draw is contained in the variable PHPFAST. The variable PHPFAST was derived
as follows: characters 1-2 (PH) refer to "phlebotomy," character 3 (P)
refers to "primary," characters 4-8 (FAST) refer to an abbreviation for
"fasting."
CODE TOPIC
AT Alanine aminotransferase (from biochemistry profile)
AM Albumin (from biochemistry profile)
AP Alkaline phosphatase (from biochemistry profile)
AL Allergy skin test
AC Alpha carotene
AN Anisocytosis
AA Apolipoprotein (AI)
AB Apolipoprotein (B)
AS Aspartate aminotransferase (from biochemistry profile)
LA Atypical lymphocyte
AU Audiometry
BA Band
BO Basophil
BS Basophilic stippling
BC Beta carotene
BX Beta cryptoxanthin
BL Blast
BU Blood urea nitrogen (BUN) (from biochemistry profile)
BM Body measurements
BD Bone densitometry
C1 C-peptide (first venipuncture)
C2 C-peptide (second venipuncture)
CR C-reactive protein
UD Cadmium
CN Central nervous system function evaluation
CL Chloride (from biochemistry profile)
CO Cotinine
CE Creatinine (serum)(from biochemistry profile)
UR Creatinine (urine)
DM Demographic
DE Dental examination
MQ Diagnostic interview schedule
DR Dietary recall (total nutrient intakes)
EO Eosinophil
EP Erythrocyte protoporphyrin
FR Ferritin
FB Fibrinogen
RB Folate (RBC)
FO Folate (serum)
FH Follicle stimulating hormone (FSH)
FP Fundus photography
CODE TOPIC
GG Gamma glutamyl transferase (GGT) (from biochemistry profile)
GU Gallbladder ultrasonography
GB Globulin (from biochemistry profile)
G1 Glucose (first venipuncture)
G2 Glucose (second venipuncture)
SG Glucose (from biochemistry profile)
GH Glycated hemoglobin
GR Granulocyte
C3 HCO3 (Bicarbonate)(from biochemistry profile)
HD HDL cholesterol
HP Helicobacter pylori antibody
HT Hematocrit
HG Hemoglobin
AH Hepatitis A antibody (HAV)
HB Hepatitis B core antibody (anti-HBc)
SS Hepatitis B surface antibody (anti-HBs)
SA Hepatitis B surface antigen (HBsAg)
HC Hepatitis C antibody (HCV)
DH Hepatitis D antibody (HDV)
H1 Herpes 1 antibody
H2 Herpes 2 antibody
HX Home examination (general)
HF Household family questionnaire
HA Household adult questionnaire
HQ Household questionnaire variables (composite)
HS Household screener questionnaire
HY Household youth questionnaire
HZ Hypochromia
I1 Insulin (first venipuncture)
I2 Insulin (second venipuncture)
UI Iodine (urine)
FE Iron
SF Iron (from biochemistry profile)
LD Lactate dehydrogenase (from biochemistry profile)
L1 Latex antibody
LC LDL cholesterol (calculated)
PB Lead
LP Lipoprotein (a)
LH Luteinizing hormone
LU Lutein/zeaxanthin
LY Lycopene
LM Lymphocyte
MR Macrocyte
MC Mean cell hemoglobin (MCH)
MH Mean cell hemoglobin concentration (MCHC)
MV Mean cell volume (MCV)
PV Mean platelet volume
MA MEC adult questionnaire
MX MEC examination (general)
FF Dietary food frequency (ages 12-16 years)
MP MEC proxy questionnaire
MY MEC youth questionnaire
ME Metamyelocyte
MI Microcyte
MO Monocyte
MN Mononuclear cell
ML Myelocyte
CODE TOPIC
IC Normalized calcium (derived from ionized calcium)
OS Osmolality (from biochemistry profile)
PH Phlebotomy data collected in MEC (e.g., questions)
PS Phosphorus (from biochemistry profile)
PF Physical function evaluation
PE Physician's examination
PL Platelet
DW Platelet distribution width
PK Poikilocytosis
PO Polychromatophilia
SK Potassium (from biochemistry profile)
PR Promyelocyte
RC Red blood cell count (RBC)
RW Red cell distribution width (RDW)
RE Retinyl esters
RF Rheumatoid factor antibody
RU Rubella antibody
WT Sample weights
SE Selenium
SI Sickle cell
NA Sodium (from biochemistry profile)
SH Spherocyte
SP Spirometry
SD Survey design
TT Target cell
TE Tetanus
TB Total bilirubin (from biochemistry profile)
CA Total calcium
SC Total calcium (from biochemistry profile)
TC Total cholesterol
CH Total cholesterol (from biochemistry profile)
TI Total iron binding capacity (TIBC)
TP Total protein (from biochemistry profile)
TX Toxic granulation
TO Toxoplasmosis antibody
PX Transferrin saturation
TG Triglycerides
TR Triglycerides (from biochemistry profile)
TY Tympanometry
UA Uric acid (from biochemistry profile)
UB Urinary albumin
VU Vacuolated cells
VR Varicella antibody
VA Vitamin A
VB Vitamin B12
VC Vitamin C
VE Vitamin E
WC White blood cell count (WBC)
WW WISC/WRAT cognitive test
GENERAL REFERENCES
Delgado JL, Johnson CL, Roy I, Trevino FM. Hispanic Health and Nutrition
Examination Survey: methodological considerations. Amer J Pub Health
80(suppl.):6-10. 1990.
Engel A, Murphy RS, Maurer K, Collins E. Plan and operation of the HANES I
Augmentation Survey of Adults 25-74 Years, United States, 1974-75.
National Center for Health Statistics. Vital Health Stat 1(14). 1978.
Freeman DH, Freeman JL, Brock DB, Koch GG. Strategies in the multivariate
analysis of data from complex surveys II: an application to the United
States National Health Interview Survey. Int Stat Rev 40(3):317-30. 1976.
Khare M, Mohadjer LK, Ezzati-Rice TM, Waksberg J. An evaluation of
nonresponse bias in NHANES III (1988-91). 1994 Proceedings of the Survey
Research Methods section of the American Statistical Association. 1994.
Landis JR, Lepkowski JM, Eklund SA, Stehouwer SA. A statistical
methodology for analyzing data from a complex survey, the first National
Health and Nutrition Examination Survey. National Center for Health
Statistics. Vital Health Stat 2(92). 1982.
McDowell A, Engel A, Massey JT, Maurer K. Plan and operation of the second
National Health and Nutrition Examination Survey, 1976-80. National Center
for Health Statistics. Vital Health Stat 1(15). 1981.
Miller HW. Plan and operation of the Health and Nutrition Examination
Survey, United States, 1971-1973. National Center for Health Statistics.
Vital Health Stat 1(10a) and (10b). 1973.
National Center for Health Statistics. Plan and initial program of the
Health Examination Survey. Vital Health Stat 1(4). 1965.
National Center for Health Statistics. Plan and operation of a health
examination survey of U.S. youths 12-17 years of age. Vital Health Stat
1(8). 1969.
National Center for Health Statistics. Plan and operation of the Hispanic
Health and Nutrition Examination Survey, 1982-84. Vital Health Stat 1(19).
1985.
National Center for Health Statistics. Plan and operation of the Third
National Health and Nutrition Examination Survey, 1988-94. Vital Health
Stat 1(32). 1994.
National Center for Health Statistics. Plan, operation, and response
results of a program of children's examinations. Vital Health Stat 1(5).
1967.
Shah BV, Barnwell BG, Bieler GS. SUDAAN User's Manual: Software for
Analysis of Correlated Data. Research Triangle Park, NC: Research Triangle
Institute. Release 6.04. 1995.
Skinner CJ. Aggregated analysis: standard errors and significance tests.
In: Skinner CJ, Holt D, Smith TMF, eds. Analysis of complex surveys. New
York: John Wiley and Sons, Inc. 1989.
U.S. Department of Health and Human Services (DHHS). National Center for
Health Statistics. NHANES III reference manuals and reports (CD-ROM).
Hyattsville, MD: Centers for Disease Control and Prevention, 1996.
Available from National Technical Information Service (NTIS), Springfield,
VA. Acrobat .PDF format; includes access software: Adobe Systems, Inc.
Acrobat Reader 2.1.
Westat, Inc. A User's Guide to WesVarPC. Rockville, MD. Westat, Inc.
1996.
Yetley E, Johnson C. Nutritional applications of the Health and Nutrition
Examination Surveys (HANES). Annu Rev Nutr 7:441-63. 1987.
NHANES III LABORATORY DATA FILE
General Information
Introduction
The Laboratory Data File contains data from the urine collection and
venipuncture components of the examination, including almost all laboratory
test results (blood and urine) available to date. The exceptions are
discussed elsewhere in this documentation. In addition, auxiliary
information such as how long the examinee fasted, the time of day of the
venipuncture, and the conditions precluding venipuncture has been included.
This documentation presents information that should be reviewed before
proceeding with data analysis.
The documentation pertaining specifically to the Laboratory Data File is
divided into four main sections. The first section, "General Information,"
provides information about the contents of the Laboratory Data File. The
second section, "Data File Index," includes a brief description of all the
variables on the data set and shows the standard name of each variable and
its position in the data set. The third section, "Item Descriptions,
Codes, Counts, and Notes" provides for each component a description, the
standard variable name and a brief description of the values that variable
can take on, a count of the frequency of occurrence of each value, notes by
variable, and appendices as necessary. "References" are provided in the
fourth section.
Blood and urine specimens were collected on examinees aged one year and
older at the mobile examination center (MEC). For those examinees aged one
year and older who did not travel to the MEC, only blood specimens were
collected during the Home Examination (HE). Hematologic profiles were
completed for all examinees, and specified laboratory tests were performed
upon each specimen based on the examinee's age and sex. Only a limited
number of tests were performed on specimens collected during the Home
Examination. Appendix 1 lists the laboratory tests by specimen type, age
group, sex, and whether the specimen was collected in the Home Examination.
The analysis of NHANES III laboratory data must be conducted with the key
survey design and basic demographic variables. The NHANES III Household
Youth Questionnaire Data File (ages two months to 16 years) and the NHANES
III Household Adult Questionnaire Data File (ages 17 years and older)
contain demographic data, health indicators, and other related information
collected during household interviews. They also contain all survey design
variables and sample weights for these age groups. These two household
questionnaire files may be linked to the laboratory data file using the
unique survey participant (sample person) identifier SEQN.
Examinee Screening
Prior to the phlebotomy (venipuncture), a questionnaire was administered to
determine an examinee's eligibility for all phlebotomy procedures
(including venipuncture and the oral glucose tolerance test). It included
questions to determine if it was safe to perform the venipuncture, to
document and determine fasting compliance, and to aid in analyzing the
results of the laboratory tests performed. Examinees reporting hemophilia or
recent cancer chemotherapy treatment were excluded from the venipuncture.
For those examinees, the laboratory test results fields for all blood-based
laboratory tests were left blank. Because examinees reporting current
insulin therapy were excluded from receiving the oral glucose tolerance test
(OGTT), the plasma glucose (G2P), serum insulin (I2P) and serum C-peptide
(C2P) results from the second venipuncture were left blank as well.
Although examinees aged 12 years and older were instructed to fast for
10-16 hours prior to the morning examination or for six hours before the
afternoon or evening examination, the instructions were not followed
uniformly. Laboratory test results and the duration of the fast have been
included on the data file regardless of the examinee's fasting compliance.
Analysts should consider whether fasting status is crucial before undertaking
analyses. Examinees who reported insulin use during the household
interview were not instructed to fast.
Specimen Collection and Processing Procedures
Detailed specimen collection and processing instructions are discussed in
the Manual for Medical Technicians (U.S. DHHS, 1996). Vials were stored
under appropriate refrigerated (4-8 degrees Centigrade) or frozen (-20
degrees Centigrade) conditions until they were shipped to analytical
laboratories for testing. The analytical methods used by each of the
participating laboratories are described in the Laboratory Procedures Used
for NHANES III (U.S. DHHS, 1996). The manual contains quality control
graphs and statistical summary information for each laboratory test at the
end of the laboratory method description.
Oral glucose tolerance testing: During NHANES III, the OGTT was conducted
on MEC examinees aged 40-74 years. The protocol included two timed
venipunctures and a glucose drink. Two glucose drinks were used to measure
an examinee's ability to metabolize glucose -- Dextol(TM) and Trutol(TM).
After the first venipuncture, the examinee drank the glucose drink, and a
second venipuncture was performed approximately two hours later.
Examiner Training and Quality Control
The NHANES III laboratory staff consisted of medical technologists and
phlebotomists. The medical technologists held baccalaureates in medical
technology. Both they and the phlebotomists were certified by the American
Society for Clinical Pathologists or by a similar organization.
All laboratory staff completed comprehensive training in standardized
laboratory procedures before they began working in the MEC. The MEC
phlebotomists completed comprehensive training in pediatric phlebotomy
techniques, including instruction by a pediatric nurse practitioner.
Laboratory team performance was monitored using several techniques. NCHS
and contract consultants used a structured quality assurance evaluation
during unscheduled visits to evaluate both the quality of the laboratory work
and the quality-control procedures. Each laboratory staff person was
observed for equipment operation, specimen collection and preparation, and
testing procedures, and constructive feedback was given to each team. Formal
retraining sessions were conducted annually to ensure that required skill
levels were maintained.
Laboratory Protocol Changes from 1988 to 1994
Most laboratory tests were performed for the entire six years of NHANES
III. Exceptions are detailed below. Apolipoprotein AI and B tests were
included during 1988-1991 only. Lipoprotein(a), Vitamin B12, and antibody
tests for immunoglobulin E, rubella, varicella, and toxoplasmosis were
conducted during 1991-1994. For the 1991-1994 period, the OGTT procedure was
modified to add tests for C-peptide and insulin on specimens from the second
venipuncture. For statistical analyses of these laboratory test results, the
appropriate Phase 1 or Phase 2 sample weight should be used.
Incomplete Data Release
At the time of this data release, some laboratory test results were not
available. Tests for which results were unavailable included vitamin D,
immunoglobulin E, diphtheria antitoxin, measles antibody, homocysteine,
periodontal pathogens, thyroxine, thyroid stimulating hormone,
antithyroglobulin antibody, antimicrosomal antibody, and methylmalonic
acid. Cotinine test results for 1988-1991 have been included in this
laboratory data file. Cotinine testing is still being carried out for
1991-1994, and the laboratory test results will be released at a future date.
Results from urine pregnancy tests are included in the NHANES III Examination
Data File, rather than in the Laboratory Data File.
Serologic testing for human immunodeficiency virus (HIV) antibody and urine
testing for drugs of abuse were performed anonymously. The drugs of abuse
for which examinees were tested were cocaine, marijuana, opiates,
phencyclidine, and amphetamines. To maintain anonymity, the examinee's
serum and urine were labeled with a random identifying number, and limited
demographic data were linked to that number. The new identifier was not
linked to the original sample identifier. Therefore, these data cannot be
linked to other NHANES III data. The HIV test was performed from 1988
through 1994; the urine drug testing was done from 1991 through 1994.
Because of the limited analytic potential of the HIV and drug data, this
file is not included in this data release.
Data Preparation and Processing
For laboratory tests with a lower detection limit, results below the lower
detection limit were replaced with a value equal to the detection limit
divided by the square root of two. This value was created to help the user
distinguish a nondetectable laboratory test result from a measured
laboratory test result. Appendix 2 documents the detection limit for each
laboratory test.
The SI unit (le Systeme International d Unites) is an outgrowth of the
metric system that has been used throughout most of the world. In addition
to providing a uniform international system of units of measurement, a
uniform style is prescribed. Laboratory test results not originally reported
in SI units were converted to SI units if applicable. Conversion factors,
the format of the NHANES and SI results, and NHANES and SI units of measure
are in Appendix 3. In converting NHANES III data to SI units, the goal was
to preserve the level of detail reported by the laboratories in the original
laboratory test result. Therefore, the number of significant digits in the
laboratory test results data may be different from that in published
references.
The Laboratory Data File contains laboratory test results for glucose
(G1P), triglycerides (TGP), cholesterol (TCP), and iron (FEP) measured by
contract laboratories using reference analytic methods. For these methods,
consult the Laboratory Procedures Used for NHANES III (U.S. DHHS, 1996).
However, the biochemistry profile also included measurements of these
analytes. In general, for most analyses, the appropriate variables to use
are G1P, TGP, TCP and FEP. The values from the biochemistry profile (SGP,
CHP, TRP, SFP) should not be used routinely.
The definition of a reference method by the National Committee for Clinical
Laboratory Standards (NCCLS) is "a thoroughly investigated method in which
exact and clear descriptions of the necessary conditions and procedures are
given for the accurate determination of one or more property values; the
documented accuracy and precision of the method are commensurate with the
method's use for assessing the accuracy of other methods for measuring the
same property values or for assigning reference method values to reference
materials" (NCCLS, 1991).
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
DEMOGRAPHIC DATA
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
Sample person identification number ......... SEQN 1-5
Family sequence number ...................... DMPFSEQ 6-10
Examination/interview Status ................ DMPSTAT 11
Race-ethnicity .............................. DMARETHN 12
Race ........................................ DMARACER 13
Ethnicity ................................... DMAETHNR 14
Sex ......................................... HSSEX 15
Age at interview (Screener) ................. HSAGEIR 16-17
Age at interview - unit (Screener) .......... HSAGEU 18
Age in months at interview (screener) ....... HSAITMOR 19-22
Family size (persons in family) ............. HSFSIZER 23-24
Household size (persons in dwelling) ........ HSHSIZER 25-26
County code ................................. DMPCNTYR 27-29
FIPS code for State ......................... DMPFIPSR 30-31
Rural/urban code based on USDA code ......... DMPMETRO 32
Census region, weighting(Texas in south) .... DMPCREGN 33
Poverty Income Ratio (unimputed income) ..... DMPPIR 34-39
SURVEY DESIGN DATA
Phase of NHANES III survey .................. SDPPHASE 40
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Total NHANES III pseudo-PSU ................. SDPPSU6 41
Total NHANES III pseudo-stratum ............. SDPSTRA6 42-43
Pseudo-PSU for phase 1 ...................... SDPPSU1 44
Pseudo-stratum for phase 1 .................. SDPSTRA1 45-46
Pseudo-PSU for phase 2 ...................... SDPPSU2 47
Pseudo-stratum for phase 2 .................. SDPSTRA2 48-49
SAMPLING WEIGHTS - TOTAL NHANES III (1988-94)
Total interviewed sample final weight ....... WTPFQX6 50-58
Total MEC-examined sample final weight ...... WTPFEX6 59-67
Total M+H examined sample final weight ...... WTPFHX6 68-76
Total allergy subsample final weight ........ WTPFALG6 77-85
Total CNS subsample final weight ............ WTPFCNS6 86-94
Total morning subsample final wgt ........... WTPFSD6 95-103
Total afternoon/eve subsample final wgt ..... WTPFMD6 104-112
Total M+H morning subsample final wgt ....... WTPFHSD6 113-121
Total M+H afternoon subsample final wgt ..... WTPFHMD6 122-130
SAMPLING WEIGHTS - NHANES III PHASE 1 (1988-91)
Phase 1 interviewed sample final wgt ........ WTPFQX1 131-139
Phase 1 MEC examined sample final wgt ....... WTPFEX1 140-148
Phase 1 M+H examined sample final wgt ....... WTPFHX1 149-157
Phase 1 allergy subsample final wgt ......... WTPFALG1 158-166
Phase 1 CNS subsample final wgt ............. WTPFCNS1 167-175
Phase 1 morning sess subsample final wgt .... WTPFSD1 176-184
Phase 1 aft/eve subsample final wgt ......... WTPFMD1 185-193
Phase 1 morning M+H subsample final wgt ..... WTPFHSD1 194-202
Phase 1 aft/eve M+H subsample final wgt ..... WTPFHMD1 203-211
SAMPLING WEIGHTS - NHANES III PHASE 2 (1991-94)
Phase 2 interviewed sample final wgt ........ WTPFQX2 212-220
Phase 2 MEC examined sample final wgt ....... WTPFEX2 221-229
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Phase 2 M+H examined sample final wgt ....... WTPFHX2 230-238
Phase 2 allergy subsample final wgt ......... WTPFALG2 239-247
Phase 2 CNS subsample final wgt ............. WTPFCNS2 248-256
Phase 2 morning sess subsample final wgt .... WTPFSD2 257-265
Phase 2 aft/eve subsample final wgt ......... WTPFMD2 266-274
Phase 2 morning M+H subsample final wgt ..... WTPFHSD2 275-283
Phase 2 aft/eve M+H subsample final wgt ..... WTPFHMD2 284-292
FAY'S BRR REPLICATE INTERVIEW WEIGHTS - TOTAL NHANES III (1988-94)
Replicate 1 final interview weight .......... WTPQRP1 293-301
Replicate 2 final interview weight .......... WTPQRP2 302-310
Replicate 3 final interview weight .......... WTPQRP3 311-319
Replicate 4 final interview weight .......... WTPQRP4 320-328
Replicate 5 final interview weight .......... WTPQRP5 329-337
Replicate 6 final interview weight .......... WTPQRP6 338-346
Replicate 7 final interview weight .......... WTPQRP7 347-355
Replicate 8 final interview weight .......... WTPQRP8 356-364
Replicate 9 final interview weight .......... WTPQRP9 365-373
Replicate 10 final interview weight ......... WTPQRP10 374-382
Replicate 11 final interview weight ......... WTPQRP11 383-391
Replicate 12 final interview weight ......... WTPQRP12 392-400
Replicate 13 final interview weight ......... WTPQRP13 401-409
Replicate 14 final interview weight ......... WTPQRP14 410-418
Replicate 15 final interview weight ......... WTPQRP15 419-427
Replicate 16 final interview weight ......... WTPQRP16 428-436
Replicate 17 final interview weight ......... WTPQRP17 437-445
Replicate 18 final interview weight ......... WTPQRP18 446-454
Replicate 19 final interview weight ......... WTPQRP19 455-463
Replicate 20 final interview weight ......... WTPQRP20 464-472
Replicate 21 final interview weight ......... WTPQRP21 473-481
Replicate 22 final interview weight ......... WTPQRP22 482-490
Replicate 23 final interview weight ......... WTPQRP23 491-499
Replicate 24 final interview weight ......... WTPQRP24 500-508
Replicate 25 final interview weight ......... WTPQRP25 509-517
Replicate 26 final interview weight ......... WTPQRP26 518-526
Replicate 27 final interview weight ......... WTPQRP27 527-535
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Replicate 28 final interview weight ......... WTPQRP28 536-544
Replicate 29 final interview weight ......... WTPQRP29 545-553
Replicate 30 final interview weight ......... WTPQRP30 554-562
Replicate 31 final interview weight ......... WTPQRP31 563-571
Replicate 32 final interview weight ......... WTPQRP32 572-580
Replicate 33 final interview weight ......... WTPQRP33 581-589
Replicate 34 final interview weight ......... WTPQRP34 590-598
Replicate 35 final interview weight ......... WTPQRP35 599-607
Replicate 36 final interview weight ......... WTPQRP36 608-616
Replicate 37 final interview weight ......... WTPQRP37 617-625
Replicate 38 final interview weight ......... WTPQRP38 626-634
Replicate 39 final interview weight ......... WTPQRP39 635-643
Replicate 40 final interview weight ......... WTPQRP40 644-652
Replicate 41 final interview weight ......... WTPQRP41 653-661
Replicate 42 final interview weight ......... WTPQRP42 662-670
Replicate 43 final interview weight ......... WTPQRP43 671-679
Replicate 44 final interview weight ......... WTPQRP44 680-688
Replicate 45 final interview weight ......... WTPQRP45 689-697
Replicate 46 final interview weight ......... WTPQRP46 698-706
Replicate 47 final interview weight ......... WTPQRP47 707-715
Replicate 48 final interview weight ......... WTPQRP48 716-724
Replicate 49 final interview weight ......... WTPQRP49 725-733
Replicate 50 final interview weight ......... WTPQRP50 734-742
Replicate 51 final interview weight ......... WTPQRP51 743-751
Replicate 52 final interview weight ......... WTPQRP52 752-760
FAY'S BRR REPLICATE EXAMINATION WEIGHTS - TOTAL NHANES III (1988-94)
Replicate 1 final exam weight ............... WTPXRP1 761-769
Replicate 2 final exam weight ............... WTPXRP2 770-778
Replicate 3 final exam weight ............... WTPXRP3 779-787
Replicate 4 final exam weight ............... WTPXRP4 788-796
Replicate 5 final exam weight ............... WTPXRP5 797-805
Replicate 6 final exam weight ............... WTPXRP6 806-814
Replicate 7 final exam weight ............... WTPXRP7 815-823
Replicate 8 final exam weight ............... WTPXRP8 824-832
Replicate 9 final exam weight ............... WTPXRP9 833-841
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Replicate 10 final exam weight .............. WTPXRP10 842-850
Replicate 11 final exam weight .............. WTPXRP11 851-859
Replicate 12 final exam weight .............. WTPXRP12 860-868
Replicate 13 final exam weight .............. WTPXRP13 869-877
Replicate 14 final exam weight .............. WTPXRP14 878-886
Replicate 15 final exam weight .............. WTPXRP15 887-895
Replicate 16 final exam weight .............. WTPXRP16 896-904
Replicate 17 final exam weight .............. WTPXRP17 905-913
Replicate 18 final exam weight .............. WTPXRP18 914-922
Replicate 19 final exam weight .............. WTPXRP19 923-931
Replicate 20 final exam weight .............. WTPXRP20 932-940
Replicate 21 final exam weight .............. WTPXRP21 941-949
Replicate 22 final exam weight .............. WTPXRP22 950-958
Replicate 23 final exam weight .............. WTPXRP23 959-967
Replicate 24 final exam weight .............. WTPXRP24 968-976
Replicate 25 final exam weight .............. WTPXRP25 977-985
Replicate 26 final exam weight .............. WTPXRP26 986-994
Replicate 27 final exam weight .............. WTPXRP27 995-1003
Replicate 28 final exam weight .............. WTPXRP28 1004-1012
Replicate 29 final exam weight .............. WTPXRP29 1013-1021
Replicate 30 final exam weight .............. WTPXRP30 1022-1030
Replicate 31 final exam weight .............. WTPXRP31 1031-1039
Replicate 32 final exam weight .............. WTPXRP32 1040-1048
Replicate 33 final exam weight .............. WTPXRP33 1049-1057
Replicate 34 final exam weight .............. WTPXRP34 1058-1066
Replicate 35 final exam weight .............. WTPXRP35 1067-1075
Replicate 36 final exam weight .............. WTPXRP36 1076-1084
Replicate 37 final exam weight .............. WTPXRP37 1085-1093
Replicate 38 final exam weight .............. WTPXRP38 1094-1102
Replicate 39 final exam weight .............. WTPXRP39 1103-1111
Replicate 40 final exam weight .............. WTPXRP40 1112-1120
Replicate 41 final exam weight .............. WTPXRP41 1121-1129
Replicate 42 final exam weight .............. WTPXRP42 1130-1138
Replicate 43 final exam weight .............. WTPXRP43 1139-1147
Replicate 44 final exam weight .............. WTPXRP44 1148-1156
Replicate 45 final exam weight .............. WTPXRP45 1157-1165
Replicate 46 final exam weight .............. WTPXRP46 1166-1174
Replicate 47 final exam weight .............. WTPXRP47 1175-1183
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Replicate 48 final exam weight .............. WTPXRP48 1184-1192
Replicate 49 final exam weight .............. WTPXRP49 1193-1201
Replicate 50 final exam weight .............. WTPXRP50 1202-1210
Replicate 51 final exam weight .............. WTPXRP51 1211-1219
Replicate 52 final exam weight .............. WTPXRP52 1220-1228
HOUSEHOLD YOUTH QUESTIONNAIRE (HYQ)
Age in months at youth interview ............ HYAITMO 1229-1232
MEC EXAMINATION
Language used by SP in MEC .................. MXPLANG 1233
Session for MEC examination ................. MXPSESSR 1234
Day of week of MEC exam ..................... MXPTIDW 1235
Age in months at MEC exam ................... MXPAXTMR 1236-1239
HOME EXAMINATION
Day of week of home exam .................... HXPTIDW 1240
Age in months at home exam .................. HXPAXTMR 1241-1244
Session for home examination ................ HXPSESSR 1245
PHLEBOTOMY SCREENING QUESTIONNAIRE
Language .................................... PHPLANG 1246
Do you have hemophilia? ..................... PHPHEMO 1247
Recent chemo/within the past four weeks ..... PHPCHM2 1248
Are you currently taking insulin? ........... PHPINSU 1249
Time participant last ate ................... PHPSNTI 1250-1254
Day participant last ate .................... PHPSNDA 1255
Have you had anything to drink? ............. PHPDRIN 1256
Time participant last drank ................. PHPDRTI 1257-1261
Day participant last drank .................. PHPDRDA 1262
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Length of calculated fast (in hours) ........ PHPFAST 1263-1267
Time of venipuncture ........................ PHPBEST 1268-1272
HEMATOLOGY
White blood cell count ...................... WCP 1273-1277
White blood cell count: SI .................. WCPSI 1278-1282
Lymphocyte percent (Coulter) ................ LMPPCNT 1283-1287
Mononuclear percent (Coulter) ............... MOPPCNT 1288-1292
Granulocyte percent (Coulter) ............... GRPPCNT 1293-1297
Lymphocyte number (Coulter) ................. LMP 1298-1302
Mononuclear number (Coulter) ................ MOP 1303-1306
Granulocyte number (Coulter) ................ GRP 1307-1311
Red blood cell count ........................ RCP 1312-1315
Red blood cell count: SI ................... RCPSI 1316-1319
Hemoglobin (g/dL) ........................... HGP 1320-1324
Hemoglobin: SI (g/L) ....................... HGPSI 1325-1329
Hematocrit (%) .............................. HTP 1330-1334
Hematocrit: SI (L/L=1) ..................... HTPSI 1335-1339
Mean cell volume: SI (fL) .................. MVPSI 1340-1344
Mean cell hemoglobin: SI (pg) .............. MCPSI 1345-1349
Mean cell hemoglobin concentration .......... MHP 1350-1354
Mean cell hemoglobin concentration: SI ...... MHPSI 1355-1359
Red cell distribution width (%) ............. RWP 1360-1364
Red cell distribution width:SI(fraction) .... RWPSI 1365-1370
Platelet count .............................. PLP 1371-1375
Platelet count: SI ......................... PLPSI 1376-1380
Platelet distribution width (%) ............. DWP 1381-1385
Mean platelet volume: SI (fL) .............. PVPSI 1386-1390
Segment neutrophil(percent of 100 cells) .... GRPDIF 1391-1393
Lymphocytes (percent of 100 cells) .......... LMPDIF 1394-1396
Monocytes (percent of 100 cells) ............ MOPDIF 1397-1398
Eosinophils (percent of 100 cells) .......... EOP 1399-1400
Basophils (percent of 100 cells) ............ BOP 1401-1402
Blasts (percent of 100 cells) ............... BLP 1403
Promyelocytes (percent of 100 cells) ........ PRP 1404
Metamyelocytes (percent of 100 cells) ....... MEP 1405
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Myelocytes (percent of 100 cells) ........... MLP 1406
Bands (percent of 100 cells) ................ BAP 1407-1408
Atyp lymphocytes (percent of 100 cells) ..... LAP 1409-1410
Anisocytosis (variation of cell size) ....... ANP 1411
Basophilic stippling ........................ BSP 1412
Hypochromia (stain intensity of cell) ....... HZP 1413
Poikilocytosis (cell shape variation) ....... PKP 1414
Polychromatophilia(bluish color of cell) .... POP 1415
Macrocytosis (large cell prevalence) ........ MRP 1416
Microcytosis (small cell prevalence) ........ MIP 1417
Sickle cells ................................ SIP 1418
Spherocytosis ............................... SHP 1419
Target cells ................................ TTP 1420
Toxic granulation ........................... TXP 1421
Vacuolated cells ............................ VUP 1422
GENERAL BIOCHEMISTRY TESTS
Lead (ug/dL) ................................ PBP 1423-1426
Lead: SI (umol/L) .......................... PBPSI 1427-1431
Erythrocyte protoporphyrin (ug/dL) .......... EPP 1432-1435
Erythrocyte protoporphyrin: SI (umol/L) .... EPPSI 1436-1440
Serum iron (ug/dL) .......................... FEP 1441-1443
Serum iron: SI (umol/L) .................... FEPSI 1444-1448
Serum TIBC (ug/dL) .......................... TIP 1449-1452
Serum TIBC: SI (umol/L) .................... TIPSI 1453-1458
Serum transferrin saturation (%) ............ PXP 1459-1462
Serum ferritin (ng/mL) ...................... FRP 1463-1466
Serum ferritin: SI (ug/L) .................. FRPSI 1467-1470
Serum folate (ng/mL) ........................ FOP 1471-1475
Serum folate: SI (nmol/L) .................. FOPSI 1476-1480
RBC folate (ng/mL) .......................... RBP 1481-1484
RBC folate: SI (nmol/L) .................... RBPSI 1485-1490
Serum vitamin B12 (pg/mL) ................... VBP 1491-1496
Serum vitamin B12: SI (pmol/L) ............. VBPSI 1497-1504
Serum vitamin C (mg/dL) ..................... VCP 1505-1508
Serum vitamin C: SI (mmol/L) ............... VCPSI 1509-1514
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Serum normalized calcium: SI (mmol/L) ...... ICPSI 1515-1518
Serum total calcium: SI (mmol/L) ........... CAPSI 1519-1522
Serum selenium (ng/mL) ...................... SEP 1523-1526
Serum selenium: SI (nmol/L) ................ SEPSI 1527-1530
Serum vitamin A (ug/dL) ..................... VAP 1531-1533
Serum vitamin A: SI (umol/L) ............... VAPSI 1534-1537
Serum vitamin E (ug/dL) ..................... VEP 1538-1542
Serum vitamin E: SI (umol/L) ............... VEPSI 1543-1548
Serum alpha carotene (ug/dL) ................ ACP 1549-1551
Serum alpha carotene: SI (umol/L) .......... ACPSI 1552-1555
Serum beta carotene (ug/dL) ................. BCP 1556-1559
Serum beta carotene: SI (umol/L) ............ BCPSI 1560-1564
Serum beta cryptoxanthin (ug/dL) ............ BXP 1565-1567
Serum beta cryptoxanthin: SI (umol/L) ...... BXPSI 1568-1571
Serum lutein/zeaxanthin (ug/dL) ............. LUP 1572-1574
Serum lutein/zeaxanthin: SI (umol/L) ....... LUPSI 1575-1578
Serum lycopene (ug/dL) ...................... LYP 1579-1581
Serum lycopene: SI (umol/L) ................ LYPSI 1582-1585
Serum sum retinyl esters (ug/dL) ............ REP 1586-1588
Serum sum retinyl esters: SI (umol/L) ...... REPSI 1589-1592
Serum cotinine (ng/mL) ...................... COP 1593-1597
Serum cholesterol (mg/dL) ................... TCP 1598-1600
Serum cholesterol: SI (mmol/L) ............. TCPSI 1601-1605
Serum triglycerides (mg/dL) ................. TGP 1606-1609
Serum triglycerides: SI (mmol/L) ........... TGPSI 1610-1614
Serum LDL cholesterol (mg/dL) ............... LCP 1615-1617
Serum LDL cholesterol: SI (mmol/L) ......... LCPSI 1618-1621
Serum HDL cholesterol (mg/dL) ............... HDP 1622-1624
Serum HDL cholesterol: SI (mmol/L) ......... HDPSI 1625-1628
Serum apolipoprotein AI (mg/dL) ............. AAP 1629-1631
Serum apolipoprotein AI: SI (g/L) ........... AAPSI 1632-1635
Serum apolipoprotein B (mg/dL) .............. ABP 1636-1638
Serum apolipoprotein B: SI (g/L) ............ ABPSI 1639-1642
Serum lipoprotein(a) (mg/dL) ................ LPP 1643-1645
Serum lipoprotein(a): SI (g/L) ............. LPPSI 1646-1649
Serum FSH: SI (IU/L) ....................... FHPSI 1650-1654
Serum luteinizing hormone: SI (IU/L) ........ LHPSI 1655-1658
Plasma fibrinogen (mg/dL) ................... FBP 1659-1662
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Plasma fibrinogen: SI (g/L) ................ FBPSI 1663-1666
Serum C-reactive protein (mg/dL) ............ CRP 1667-1671
ANTIBODY TESTS
Serum tetanus antibody (U/mL) ............... TEP 1672-1677
Serum hepatitis A antibody .................. AHP 1678
Serum hepatitis B core antibody ............. HBP 1679
Serum hepatitis B surface antibody .......... SSP 1680-1681
Serum hepatitis B surface antigen ........... SAP 1682
Serum hepatitis C antibody .................. HCP 1683
Serum hepatitis D antibody .................. DHP 1684
Serum herpes I antibody ..................... H1P 1685
Serum herpes II antibody .................... H2P 1686
Serum rubella antibody ...................... RUP 1687-1691
Serum rubells antibody (IU) ................. RUPUNIT 1692-1695
Serum varicella antibody .................... VRP 1696-1700
Serum toxoplasmosis antibody ................ TOP 1701-1703
Serum rheumatoid factor antibody ............ RFP 1704-1708
Serum latex antibody (IU/mL) ................ L1P 1709-1713
Serum helicobacter pylori antibody .......... HPP 1714
BIOCHEMISTRY PROFILE
Serum sodium: SI (mmol/L) .................. NAPSI 1715-1719
Serum potassium: SI (mmol/L) ............... SKPSI 1720-1723
Serum chloride: SI (mmol/L) ................ CLPSI 1724-1728
Serum bicarbonate: SI (mmol/L) ............. C3PSI 1729-1730
Serum total calcium (mg/dL) ................. SCP 1731-1734
Serum total calcium: SI (mmol/L) ............ SCPSI 1735-1739
Serum phosphorus (mg/dL) .................... PSP 1740-1743
Serum phosphorus: SI (mmol/L) ............... PSPSI 1744-1748
Serum uric acid (mg/dL) ..................... UAP 1749-1752
Serum uric acid: SI (umol/L) ............... UAPSI 1753-1757
Serum glucose (mg/dL) ....................... SGP 1758-1760
Serum glucose: SI (mmol/L) ................. SGPSI 1761-1765
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Serum blood urea nitrogen (mg/dL) ........... BUP 1766-1768
Serum blood urea nitrogen: SI (mmol/L) ..... BUPSI 1769-1773
Serum total bilirubin (mg/dL) ............... TBP 1774-1777
Serum total bilirubin: SI (umol/L) ......... TBPSI 1778-1783
Serum creatinine (mg/dL) .................... CEP 1784-1787
Serum creatinine: SI (umol/L) .............. CEPSI 1788-1793
Serum iron (ug/dL) .......................... SFP 1794-1796
Serum iron: SI (umol/L) .................... SFPSI 1797-1800
Serum cholesterol (mg/dL) ................... CHP 1801-1804
Serum cholesterol: SI (mmol/L) ............. CHPSI 1805-1810
Serum triglycerides (mg/dL) ................. TRP 1811-1814
Serum triglycerides: SI (mmol/L) ........... TRPSI 1815-1820
Aspartate aminotransferase: SI(U/L) ......... ASPSI 1821-1823
Alanine aminotransferase: SI (U/L) ......... ATPSI 1824-1826
Gamma glutamyl transferase: SI(U/L) ......... GGPSI 1827-1830
Serum lactate dehydrogenase: SI (U/L) ...... LDPSI 1831-1834
Serum alkaline phosphatase: SI (U/L) ....... APPSI 1835-1838
Serum total protein (g/dL) .................. TPP 1839-1842
Serum total protein: SI (g/L) .............. TPPSI 1843-1845
Serum albumin (g/dL) ........................ AMP 1846-1848
Serum albumin: SI (g/L) .................... AMPSI 1849-1851
Serum globulin (g/dL) ....................... GBP 1852-1854
Serum globulin: SI (g/L) ................... GBPSI 1855-1857
Serum osmolality: SI (mmol/Kg) ............. OSPSI 1858-1860
DIABETES TESTING PROFILE
Glycated hemoglobin: (%) .................... GHP 1861-1864
Glycated hemoglobin: test method ............ GHPMETH 1865
Plasma glucose (mg/dL) ...................... G1P 1866-1870
Plasma glucose: SI (mmol/L) ................ G1PSI 1871-1876
Incomplete glucose test (OGTT) code ......... G1PCODE 1877-1878
Minutes between drink and second draw ....... G1PTIM1 1879-1881
Minutes between first and second draw ....... G1PTIM2 1882-1884
Second plasma glucose (mg/dL) ............... G2P 1885-1889
Second plasma glucose: SI (mmol/L) .......... G2PSI 1890-1895
Serum C-peptide (pmol/mL) ................... C1P 1896-1900
NHANES III Laboratory Data File Index
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
Variable
Description Name Positions
------------------------------------------------------------------------
Serum C-peptide: SI (nmol/L) ................ C1PSI 1901-1905
Second serum C-peptide (pmol/mL) ............ C2P 1906-1911
Second serum C-peptide: SI (nmol/L) ......... C2PSI 1912-1917
Serum insulin (uU/mL) ....................... I1P 1918-1923
Serum insulin: SI (pmol/L) ................. I1PSI 1924-1930
Serum insulin: test kit ..................... I1P2PFLG 1931
Second serum insulin (uU/mL) ................ I2P 1932-1937
Second serum insulin: SI (pmol/L) ........... I2PSI 1938-1944
URINE TESTS
Urinary cadmium (ng/mL) ..................... UDP 1945-1949
Urinary cadmium: SI (nmol/L) ................ UDPSI 1950-1955
Urinary creatinine (mg/dL) .................. URP 1956-1960
Urinary creatinine: SI (mmol/L) ............. URPSI 1961-1964
Urinary albumin (ug/mL) ..................... UBP 1965-1970
Urinary iodine (ug/dL) ...................... UIP 1971-1977
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
FILENAME=LAB VERSION 0.91 N=29314
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1-5 Sample person identification number
SEQN 29314 00003-53623
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
6-10 Family sequence number
DMPFSEQ 29314 00001-20076
11 Examination/interview status See note
DMPSTAT 28857 2 Interviewed, MEC-examined
457 3 Interviewed, home-examined
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
12 Race-ethnicity See note
DMARETHN 10507 1 Non-Hispanic white
8756 2 Non-Hispanic black
8786 3 Mexican-American
1265 4 Other
13 Race See note
DMARACER 19180 1 White
9091 2 Black
1037 3 Other
6 8 Mexican-American of unknown race
14 Ethnicity See note
DMAETHNR 8786 1 Mexican-American
788 2 Other Hispanic
19740 3 Not Hispanic
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
15 Sex
HSSEX 13980 1 Male
15334 2 Female
16-17 Age at interview (Screener) See note
HSAGEIR 29165 01-89
149 90 90+
18 Age at interview-unit (Screener)
HSAGEU 29314 2 Years
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
19-22 Age in months (Screener) See note
HSAITMOR 29157 0012-1079
147 1080 1080+ months
10 9999 Don't know
23-24 Family size See note
HSFSIZER 3076 01
5411 02
5006 03
5950 04
4313 05
2312 06
1236 07
821 08
428 09
761 10 10+
25-26 Household size See note
HSHSIZER 2478 01
5473 02
5040 03
6041 04
4337 05
2393 06
1301 07
893 08
459 09
899 10 10+
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
27-29 County FIPS codes for United States See note
DMPCNTYR counties with populations >= 500,000
13799 001-439
15515 Blank
30-31 State FIPS codes for United States See note
DMPFIPSR counties with populations >= 500,000
359 04
4531 06
1090 12
900 17
242 25
676 26
312 29
1662 36
625 39
724 42
276 44
2044 48
358 53
15515 Blank
32 Urbanization classification based on See note
DMPMETRO USDA Rural/Urban continuum codes.
14615 1 Central counties of metro areas of
1 million population or more,
OR,
Fringe counties of metro areas of
1 million population or more
14699 2 All other areas
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD SCREENER QUESTIONNAIRE (HSQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
33 Census region See note
DMPCREGN 3740 1 Northeast
5498 2 Midwest
12639 3 South
7437 4 West
34-39 Poverty Income Ratio See note
DMPPIR 82 00.000 No reported income
26503 000.02-11.889
2729 888888 Blank but applicable
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
SURVEY DESIGN DATA
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
40 Phase of NHANES III survey See note
SDPPHASE 14833 1 1988-1991
14481 2 1991-1994
41 Total NHANES III Pseudo-PSU See note
SDPPSU6 14630 1
14684 2
42-43 Total NHANES III Pseudo-stratum See note
SDPSTRA6 29314 01-49
44 Phase 1 Pseudo-PSU See note
SDPPSU1 7633 1
7200 2
14481 Blank
45-46 Phase 1 Pseudo-stratum See note
SDPSTRA1 14833 01-23
14481 Blank
47 Phase 2 Pseudo-PSU See note
SDPPSU2 7080 1
7401 2
14833 Blank
48-49 Phase 2 Pseudo-stratum See note
SDPSTRA2 14481 01-23
14833 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
SAMPLING WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
50-58 Total NHANES III interviewed sample See note
WTPFQX6 final weight
29314 000215.53-0132278.9
59-67 Total NHANES III MEC-examined sample See note
WTPFEX6 final weight
457 000000.00
28857 000213.45-140778.72
68-76 Total NHANES III MEC and home- See note
WTPFHX6 examined final weight
29314 000214.25-139744.91
77-85 Total NHANES III allergy subsample See note
WTPFALG6 final weight
23 000000.00
12106 000213.45-288897.91
17185 Blank
86-94 Total NHANES III central nervous See note
WTPFCNS6 system (CNS) subsample final weight
12 000000.00
5662 001316.46-295826.48
23640 Blank
95-103 Total NHANES III morning session See note
WTPFSD6 MEC-examined subsample final weight
920 000000.00
9127 000450.95-292590.96
19267 Blank
104-112 Total NHANES III afternoon/evening See note
WTPFMD6 session MEC-examined subsample final
weight
697 000000.00
9497 000495.13-256201.99
19120 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
SAMPLING WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
113-121 Total NHANES III morning session MEC See note
WTPFHSD6 and home-examined subsample final
weight
791 000000.00
9254 000446.49-291479.91
19269 Blank
122-130 Total NHANES III afternoon/evening See note
WTPFHMD6 session MEC and home-examined
subsample final weight
562 000000.00
9630 000503.56-256245.36
19122 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
SAMPLING WEIGHTS - NHANES III PHASE 1 (1988-91)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
131-139 Phase 1 interviewed sample final See note
WTPFQX1 weight
14833 000461.29-264557.81
14481 Blank
140-148 Phase 1 MEC-examined sample See note
WTPFEX1 final weight
229 000000.00
14604 000527.01-281557.44
14481 Blank
149-157 Phase 1 MEC and home-examined sample See note
WTPFHX1 final weight
14833 000513.14-279489.83
14481 Blank
158-166 Phase 1 allergy subsample final weight See note
WTPFALG1 14 000000.00
6097 000821.62-577795.82
23203 Blank
167-175 Phase 1 central nervous system (CNS) See note
WTPFCNS1 subsample final weight
8 000000.00
2751 002699.84-591652.96
26555 Blank
176-184 Phase 1 morning session MEC-examined See note
WTPFSD1 subsample fnal weight
451 000000.00
4462 001111.36-585181.93
24401 Blank
185-193 Phase 1 afternoon/evening session MEC- See note
WTPFMD1 examined subsample final weight
322 000000.00
4726 001104.11-506697.07
24266 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
SAMPLING WEIGHTS - NHANES III PHASE 1 (1988-91)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
194-202 Phase 1 morning session MEC and home- See note
WTPFHSD1 examined subsample final weight
373 000000.00
4540 0001091.8-582959.83
24401 Blank
203-211 Phase 1 afternoon/evening session MEC See note
WTPFHMD1 and home-examined subsample final weight
264 000000.00
4784 001085.73-507417.05
24266 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
SAMPLING WEIGHTS - NHANES III PHASE 2 (1991-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
212-220 Phase 2 interviewed sample final See note
WTPFQX2 weight
14481 000431.06-243267.38
14833 Blank
221-229 Phase 2 MEC-examined sample See note
WTPFEX2 final weight
228 000000.00
14253 000426.91-262887.56
14833 Blank
230-238 Phase 2 MEC and home-examined sample See note
WTPFHX2 final weight
14481 0000428.5-262188.52
14833 Blank
239-247 Phase 2 allergy subsample final weight See note
WTPFALG2 9 000000.00
6009 000426.91-552445.57
23296 Blank
248-256 Phase 2 central nervous system (CNS) See note
WTPFCNS2 subsample final weight
4 000000.00
2911 002632.92-518040.33
26399 Blank
257-265 Phase 2 morning session MEC-examined See note
WTPFSD2 subsample fnal weight
469 000000.00
4665 0000901.9-550430.69
24180 Blank
266-274 Phase 2 afternoon/evening session MEC- See note
WTPFMD2 examined subsample final weight
375 000000.00
4771 000990.26-512403.98
24168 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
SAMPLING WEIGHTS - NHANES III PHASE 2 (1991-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
275-283 Phase 2 morning session MEC and home- See note
WTPFHSD2 examined subsample final weight
418 000000.00
4714 000892.98-552545.64
24182 Blank
284-292 Phase 2 afternoon/evening session MEC See note
WTPFHMD2 and home-examined subsample final weight
298 000000.00
4846 001007.13-512490.71
24170 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE INTERVIEW WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
293-301 Replicate 1 final interview weight See note
WTPQRP1 29314 000053.27-148435.02
302-310 Replicate 2 final interview weight See note
WTPQRP2 29314 000067.13-143746.82
311-319 Replicate 3 final interview weight See note
WTPQRP3 29314 000047.49-152075.62
320-328 Replicate 4 final interview weight See note
WTPQRP4 29314 000062.62-137241.93
329-337 Replicate 5 final interview weight See note
WTPQRP5 29314 000048.42-147700.94
338-346 Replicate 6 final interview weight See note
WTPQRP6 29314 0000053.1-146803.63
347-355 Replicate 7 final interview weight See note
WTPQRP7 29314 000058.18-145261.07
356-364 Replicate 8 final interview weight See note
WTPQRP8 29314 000048.23-161126.44
365-373 Replicate 9 final interview weight See note
WTPQRP9 29314 000053.27-147301.59
374-382 Replicate 10 final interview weight See note
WTPQRP10 29314 000073.37-0148125.5
383-391 Replicate 11 final interview weight See note
WTPQRP11 29314 000058.31-146940.58
392-400 Replicate 12 final interview weight See note
WTPQRP12 29314 000053.67-153958.72
401-409 Replicate 13 final interview weight See note
WTPQRP13 29314 000067.93-147395.78
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE INTERVIEW WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
410-418 Replicate 14 final interview weight See note
WTPQRP14 29314 000065.08-138456.05
419-427 Replicate 15 final interview weight See note
WTPQRP15 29314 000062.35-140673.55
428-436 Replicate 16 final interview weight See note
WTPQRP16 29314 000040.28-147603.74
437-445 Replicate 17 final interview weight See note
WTPQRP17 29314 000045.36-154057.83
446-454 Replicate 18 final interview weight See note
WTPQRP18 29314 000070.42-138896.98
455-463 Replicate 19 final interview weight See note
WTPQRP19 29314 000050.96-139447.18
464-472 Replicate 20 final interview weight See note
WTPQRP20 29314 000045.79-156365.73
473-481 Replicate 21 final interview weight See note
WTPQRP21 29314 000049.79-146241.31
482-490 Replicate 22 final interview weight See note
WTPQRP22 29314 000047.25-0154848.6
491-499 Replicate 23 final interview weight See note
WTPQRP23 29314 000037.18-148309.04
500-508 Replicate 24 final interview weight See note
WTPQRP24 29314 000057.42-141344.14
509-517 Replicate 25 final interview weight See note
WTPQRP25 29314 000044.13-145105.09
518-526 Replicate 26 final interview weight See note
WTPQRP26 29314 0000066.1-146773.53
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE INTERVIEW WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
527-535 Replicate 27 final interview weight See note
WTPQRP27 29314 000044.88-142455.25
536-544 Replicate 28 final interview weight See note
WTPQRP28 29314 000000046-148272.41
545-553 Replicate 29 final interview weight See note
WTPQRP29 29314 000079.38-153624.57
554-562 Replicate 30 final interview weight See note
WTPQRP30 29314 000058.09-151140.25
563-571 Replicate 31 final interview weight See note
WTPQRP31 29314 000051.39-159963.39
572-580 Replicate 32 final interview weight See note
WTPQRP32 29314 000066.17-132356.37
581-589 Replicate 33 final interview weight See note
WTPQRP33 29314 0000057.8-136762.37
590-598 Replicate 34 final interview weight See note
WTPQRP34 29314 000062.28-140628.16
599-607 Replicate 35 final interview weight See note
WTPQRP35 29314 000063.73-154630.49
608-616 Replicate 36 final interview weight See note
WTPQRP36 29314 000067.29-153648.69
617-625 Replicate 37 final interview weight See note
WTPQRP37 29314 000043.47-135065.98
626-634 Replicate 38 final interview weight See note
WTPQRP38 29314 000054.55-152122.87
635-643 Replicate 39 final interview weight See note
WTPQRP39 29314 000050.55-152941.69
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE INTERVIEW WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
644-652 Replicate 40 final interview weight See note
WTPQRP40 29314 000054.45-146815.92
653-661 Replicate 41 final interview weight See note
WTPQRP41 29314 000059.62-141514.78
662-670 Replicate 42 final interview weight See note
WTPQRP42 29314 000068.97-0140162.4
671-679 Replicate 43 final interview weight See note
WTPQRP43 29314 000044.04-150981.83
680-688 Replicate 44 final interview weight See note
WTPQRP44 29314 000040.36-144080.03
689-697 Replicate 45 final interview weight See note
WTPQRP45 29314 000054.74-0142465.6
698-706 Replicate 46 final interview weight See note
WTPQRP46 29314 000078.43-137838.21
707-715 Replicate 47 final interview weight See note
WTPQRP47 29314 000052.71-145055.34
716-724 Replicate 48 final interview weight See note
WTPQRP48 29314 000046.91-148787.77
725-733 Replicate 49 final interview weight See note
WTPQRP49 29314 0000072.4-148375.43
734-742 Replicate 50 final interview weight See note
WTPQRP50 29314 000070.53-159394.39
743-751 Replicate 51 final interview weight See note
WTPQRP51 29314 000054.73-0144964.3
752-760 Replicate 52 final interview weight See note
WTPQRP52 29314 000072.04-149087.24
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE EXAMINATION WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
761-769 Replicate 1 final exam weight See note
WTPXRP1 457 000000.00
28857 000054.73-164698.81
770-778 Replicate 2 final exam weight See note
WTPXRP2 457 000000.00
28857 0000067.3-164887.24
779-787 Replicate 3 final exam weight See note
WTPXRP3 457 000000.00
28857 0000048.2-0161201.8
788-796 Replicate 4 final exam weight See note
WTPXRP4 457 000000.00
28857 000067.24-149561.18
797-805 Replicate 5 final exam weight See note
WTPXRP5 457 000000.00
28857 000055.97-146312.81
806-814 Replicate 6 final exam weight See note
WTPXRP6 457 000000.00
28857 000051.48-156250.53
815-823 Replicate 7 final exam weight See note
WTPXRP7 457 000000.00
28857 000060.06-0157694.3
824-832 Replicate 8 final exam weight See note
WTPXRP8 457 000000.00
28857 0000053.1-169111.97
833-841 Replicate 9 final exam weight See note
WTPXRP9 457 000000.00
28857 000052.31-156939.22
842-850 Replicate 10 final exam weight See note
WTPXRP10 457 000000.00
28857 000072.13-0165805.2
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE EXAMINATION WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
851-859 Replicate 11 final exam weight See note
WTPXRP11 457 000000.00
28857 000053.54-154918.93
860-868 Replicate 12 final exam weight See note
WTPXRP12 457 000000.00
28857 000055.35-164023.88
869-877 Replicate 13 final exam weight See note
WTPXRP13 457 000000.00
28857 0000067.9-147355.32
878-886 Replicate 14 final exam weight See note
WTPXRP14 457 000000.00
28857 000067.04-154034.72
887-895 Replicate 15 final exam weight See note
WTPXRP15 457 000000.00
28857 000062.21-156384.73
896-904 Replicate 16 final exam weight See note
WTPXRP16 457 000000.00
28857 000000040-157994.12
905-913 Replicate 17 final exam weight See note
WTPXRP17 457 000000.00
28857 000048.34-160889.46
914-922 Replicate 18 final exam weight See note
WTPXRP18 457 000000.00
28857 0000075.2-153937.93
923-931 Replicate 19 final exam weight See note
WTPXRP19 457 000000.00
28857 000056.83-149483.14
932-940 Replicate 20 final exam weight See note
WTPXRP20 457 000000.00
28857 0000045.1-165457.71
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE EXAMINATION WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
941-949 Replicate 21 final exam weight See note
WTPXRP21 457 000000.00
28857 000055.15-152305.97
950-958 Replicate 22 final exam weight See note
WTPXRP22 457 000000.00
28857 000045.53-159746.13
959-967 Replicate 23 final exam weight See note
WTPXRP23 457 000000.00
28857 000037.51-158016.62
968-976 Replicate 24 final exam weight See note
WTPXRP24 457 000000.00
28857 000054.91-153043.54
977-985 Replicate 25 final exam weight See note
WTPXRP25 457 000000.00
28857 000043.77-155179.51
986-994 Replicate 26 final exam weight See note
WTPXRP26 457 000000.00
28857 000071.23-168273.22
995-1003 Replicate 27 final exam weight See note
WTPXRP27 457 000000.00
28857 000043.82-153212.25
1004-1012 Replicate 28 final exam weight See note
WTPXRP28 457 000000.00
28857 000045.61-147920.01
1013-1021 Replicate 29 final exam weight See note
WTPXRP29 457 000000.00
28857 000083.17-159279.49
1022-1030 Replicate 30 final exam weight See note
WTPXRP30 457 000000.00
28857 000059.05-162389.35
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE EXAMINATION WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1031-1039 Replicate 31 final exam weight See note
WTPXRP31 457 000000.00
28857 000052.61-163894.16
1040-1048 Replicate 32 final exam weight See note
WTPXRP32 457 000000.00
28857 000067.05-0149876.8
1049-1057 Replicate 33 final exam weight See note
WTPXRP33 457 000000.00
28857 000055.58-153417.47
1058-1066 Replicate 34 final exam weight See note
WTPXRP34 457 000000.00
28857 000063.45-156981.83
1067-1075 Replicate 35 final exam weight See note
WTPXRP35 457 000000.00
28857 000064.47-157897.09
1076-1084 Replicate 36 final exam weight See note
WTPXRP36 457 000000.00
28857 000067.68-171875.06
1085-1093 Replicate 37 final exam weight See note
WTPXRP37 457 000000.00
28857 000045.36-153137.39
1094-1102 Replicate 38 final exam weight See note
WTPXRP38 457 000000.00
28857 000055.94-159979.02
1103-1111 Replicate 39 final exam weight See note
WTPXRP39 457 000000.00
28857 000057.47-151920.72
1112-1120 Replicate 40 final exam weight See note
WTPXRP40 457 000000.00
28857 000057.86-157191.41
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE EXAMINATION WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1121-1129 Replicate 41 final exam weight See note
WTPXRP41 457 000000.00
28857 0000061.4-000146023
1130-1138 Replicate 42 final exam weight See note
WTPXRP42 457 000000.00
28857 000069.57-154624.02
1139-1147 Replicate 43 final exam weight See note
WTPXRP43 457 000000.00
28857 000044.35-159439.04
1148-1156 Replicate 44 final exam weight See note
WTPXRP44 457 000000.00
28857 000044.16-155951.73
1157-1165 Replicate 45 final exam weight See note
WTPXRP45 457 000000.00
28857 000059.87-147941.67
1166-1174 Replicate 46 final exam weight See note
WTPXRP46 457 000000.00
28857 000074.92-150980.02
1175-1183 Replicate 47 final exam weight See note
WTPXRP47 457 000000.00
28857 000050.64-151763.92
1184-1192 Replicate 48 final exam weight See note
WTPXRP48 457 000000.00
28857 0000045.8-156115.62
1193-1201 Replicate 49 final exam weight See note
WTPXRP49 457 000000.00
28857 000082.17-159609.54
1202-1210 Replicate 50 final exam weight See note
WTPXRP50 457 000000.00
28857 000071.97-168153.71
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
FAY'S BRR REPLICATE EXAMINATION WEIGHTS - TOTAL NHANES III (1988-94)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1211-1219 Replicate 51 final exam weight See note
WTPXRP51 457 000000.00
28857 000054.04-158632.23
1220-1228 Replicate 52 final exam weight See note
WTPXRP52 457 000000.00
28857 000073.26-158493.21
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOUSEHOLD YOUTH QUESTIONNAIRE (HYQ)
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1229-1232 Age in months at household youth See note
HYAITMO interview
11138 0012-0204
14 8888 Blank but applicable
18162 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
MEC EXAMINATION
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1233 Language used by sample person in MEC See note
MXPLANG 23936 1 English
3906 2 Spanish
3 3 Other
1469 Blank
1234 Examination session for MEC See note
MXPSESSR examinees
13643 1 Morning
9419 2 Afternoon
5795 3 Evening
457 Blank
1235 Day of week of MEC exam
MXPTIDW 2884 1 Sunday
2618 2 Monday
2503 3 Tuesday
2914 4 Wednesday
5466 5 Thursday
5082 6 Friday
7390 7 Saturday
457 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
MEC EXAMINATION
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1236-1239 Age in months at MEC exam See note
MXPAXTMR 28751 0012-1079
106 1080 1080+ months
457 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DEMOGRAPHIC DATA
------------------------------------------------------------------------
HOME EXAMINATION
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1240 Day of week of home exam
HXPTIDW 22 1 Sunday
111 2 Monday
6 3 Tuesday
16 4 Wednesday
123 5 Thursday
119 6 Friday
60 7 Saturday
28857 Blank
1241-1244 Age in months at home exam See note
HXPAXTMR 410 0252-1079
47 1080 1080+ months
28857 Blank
1245 Examination session for home See note
HXPSESSR examinees
203 1 Morning
212 2 Afternoon
38 3 Evening
4 8 Blank but applicable
28857 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
PHLEBOTOMY SCREENING QUESTIONNAIRE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1246 Language See note
PHPLANG 25009 1 English
2736 2 Spanish
1569 8 Blank but applicable
1247 Do you have hemophilia? This is a See note
PHPHEMO hereditary blood-clotting disorder
9 1 Yes, subsequent fields blank
27736 2 No
1569 8 Blank but applicable
1248 Within the past four weeks See note
PHPCHM2 have you received any cancer
chemotherapy treatment?
19 1 Yes, subsequent fields blank
27717 2 No
1569 8 Blank but applicable
9 Blank
1249 Are you currently taking insulin? See note
PHPINSU 418 1 Yes
27298 2 No
1570 8 Blank but applicable
28 Blank
1250-1254 Including your last meal and any
PHPSNTI snacks, at what time did you last
have anything at all to eat?
27701 00:00-23:59
1585 88888 Blank but applicable
28 Blank
1255 Day participant last ate
PHPSNDA 12604 1 Yesterday
15081 2 Today
16 3 Before yesterday
1585 8 Blank but applicable
28 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
PHLEBOTOMY SCREENING QUESTIONNAIRE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1256 Have you had anything to drink,
PHPDRIN other than water, after the time
you last ate?
3947 1 Yes
23754 2 No, subsequent drink fields blank
1585 8 Blank but applicable
28 Blank
1257-1261 At what time did you last have
PHPDRTI anything at all to drink other than
water?
3947 00:00-23:57
1585 88888 Blank but applicable
23782 Blank
1262 Day participant last drank
PHPDRDA 1094 1 Yesterday
2853 2 Today
1585 8 Blank but applicable
23782 Blank
1263-1267 Computed number of hours since last See note
PHPFAST ate or drank
27700 00000-39.13
1586 88888 Blank but applicable
28 Blank
1268-1272 Time of venipuncture See note
PHPBEST 27703 07:32-22:02
1583 88888 Blank but applicable
28 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
HEMATOLOGY
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1273-1277 White blood cell count See note
WCP 26372 01.75-71.35
2914 88888 Blank but applicable
28 Blank
1278-1282 White blood cell count: SI
WCPSI 26372 01.75-71.35
2914 88888 Blank but applicable
28 Blank
1283-1287 Lymphocyte percent (Coulter)
LMPPCNT 26370 003.2-083.2
2916 88888 Blank but applicable
28 Blank
1288-1292 Mononuclear percent (Coulter)
MOPPCNT 25924 00000-37.55
3362 88888 Blank but applicable
28 Blank
1293-1297 Granulocyte percent (Coulter)
GRPPCNT 25925 010.9-093.9
3361 88888 Blank but applicable
28 Blank
1298-1302 Lymphocyte number (Coulter) See note
LMP 26370 00.35-048.1
2916 88888 Blank but applicable
28 Blank
1303-1306 Mononuclear number (Coulter) See note
MOP 25924 0000-06.4
3362 8888 Blank but applicable
28 Blank
1307-1311 Granulocyte number (Coulter) See note
GRP 25925 000.2-023.4
3361 88888 Blank but applicable
28 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
HEMATOLOGY
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1312-1315 Red blood cell count See note
RCP 26370 1.69-6.84
2916 8888 Blank but applicable
28 Blank
1316-1319 Red blood cell count: SI
RCPSI 26370 1.69-6.84
2916 8888 Blank but applicable
28 Blank
1320-1324 Hemoglobin (g/dL) See note
HGP 26372 04.95-019.6
2914 88888 Blank but applicable
28 Blank
1325-1329 Hemoglobin: SI (g/L)
HGPSI 26372 049.5-00196
2914 88888 Blank but applicable
28 Blank
1330-1334 Hematocrit (%) See note
HTP 26370 016.6-057.6
2916 88888 Blank but applicable
28 Blank
1335-1339 Hematocrit: SI (L/L=1)
HTPSI 26370 0.166-0.576
2916 88888 Blank but applicable
28 Blank
1340-1344 Mean cell volume: SI (fL) See note
MVPSI 26371 051.2-122.8
2915 88888 Blank but applicable
28 Blank
1345-1349 Mean cell hemoglobin: SI (pg) See note
MCPSI 26369 013.6-053.6
2917 88888 Blank but applicable
28 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
HEMATOLOGY
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1350-1354 Mean cell hemoglobin concentration See note
MHP (g/dL)
26369 25.95-52.35
2917 88888 Blank but applicable
28 Blank
1355-1359 Mean cell hemoglobin
MHPSI concentration: SI (g/L)
26369 259.5-523.5
2917 88888 Blank but applicable
28 Blank
1360-1364 Red cell distribution width (%)
RWP 26372 007.8-31.95
2914 88888 Blank but applicable
28 Blank
1365-1370 Red cell distribution width: SI
RWPSI (fraction)
26372 00.078-0.3195
2914 888888 Blank but applicable
28 Blank
1371-1375 Platelet count See note
PLP 26367 014.5-00981
2919 88888 Blank but applicable
28 Blank
1376-1380 Platelet count: SI
PLPSI 26367 014.5-00981
2919 88888 Blank but applicable
28 Blank
1381-1385 Platelet distribution width (%)
DWP 26200 005.8-24.65
3086 88888 Blank but applicable
28 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
HEMATOLOGY
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1386-1390 Mean platelet volume: SI (fL)
PVPSI 26373 00003-00043
2913 88888 Blank but applicable
28 Blank
1391-1393 Segmented neutrophils (percent of 100 See note
GRPDIF cells)
8150 007-090
2276 888 Blank but applicable
18888 Blank
1394-1396 Lymphocytes (percent of 100 cells) See note
LMPDIF 8150 004-088
2276 888 Blank but applicable
18888 Blank
1397-1398 Monocytes (percent of 100 cells) See note
MOPDIF 8150 00-23
2276 88 Blank but applicable
18888 Blank
1399-1400 Eosinophils (percent of 100 cells) See note
EOP 8150 00-51
2276 88 Blank but applicable
18888 Blank
1401-1402 Basophils (percent of 100 cells) See note
BOP 8150 00-22
2276 88 Blank but applicable
18888 Blank
1403 Blasts (percent of 100 cells) See note
BLP 8150 0
2276 8 Blank but applicable
18888 Blank
1404 Promyelocytes (percent of 100 cells) See note
PRP 8150 0
2276 8 Blank but applicable
18888 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
HEMATOLOGY
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1405 Metamyelocytes (percent of 100 cells) See note
MEP 8150 0-2
2276 8 Blank but applicable
18888 Blank
1406 Myelocytes (percent of 100 cells) See note
MLP 8150 0-1
2276 8 Blank but applicable
18888 Blank
1407-1408 Bands (percent of 100 cells) See note
BAP 8150 00-22
2276 88 Blank but applicable
18888 Blank
1409-1410 Atypical lymphocytes (percent of 100 See note
LAP cells)
8150 00-28
2276 88 Blank but applicable
18888 Blank
1411 Anisocytosis (variation of cell size) See note
ANP 6120 0 Normal
2030 1-4 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1412 Basophilic stippling See note
BSP 8047 0 Normal
103 1-3 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1413 Hypochromia (stain intensity of cell) See note
HZP 6891 0 Normal
1259 1-4 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
HEMATOLOGY
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1414 Poikilocytosis (cell shape variation) See note
PKP 7067 0 Normal
1083 1-4 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1415 Polychromatophilia (bluish color of cell)See note
POP 7231 0 Normal
919 1-3 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1416 Macrocytosis (large cell prevalence) See note
MRP 7569 0 Normal
581 1-3 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1417 Microcytosis (small cell prevalence) See note
MIP 6873 0 Normal
1277 1-4 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1418 Sickle cells See note
SIP 8135 0 Normal
15 1-3 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1419 Spherocytosis See note
SHP 7479 0 Normal
671 1-4 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1420 Target cells See note
TTP 7620 0 Normal
530 1-4 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
HEMATOLOGY
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1421 Toxic granulation See note
TXP 7839 0 Normal
311 1-4 Gradation to abnormal
2276 8 Blank but applicable
18888 Blank
1422 Vacuolated cells See note
VUP 8150 0 Normal
2276 8 Blank but applicable
18888 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1423-1426 Lead (ug/dL)
PBP 2342 00.7 Below level of detection
24476 0001-71.8
2468 8888 Blank but applicable
28 Blank
1427-1431 Lead: SI (umol/L)
PBPSI 2342 0.034 Below level of detection
24476 0.048-3.465
2468 88888 Blank but applicable
28 Blank
1432-1435 Protoporphyrin (ug/dL RBC)
EPP 26706 0003-1008
2580 8888 Blank but applicable
28 Blank
1436-1440 Protoporphyrin: SI (umol/L RBC)
EPPSI 26706 00.05-17.94
2580 88888 Blank but applicable
28 Blank
1441-1443 Serum iron (ug/dL) See note
FEP 26479 004-338
2807 888 Blank but applicable
28 Blank
1444-1448 Serum iron: SI (umol/L)
FEPSI 26479 00.72-60.54
2807 88888 Blank but applicable
28 Blank
1449-1452 Serum TIBC (ug/dL)
TIP 25802 0069-0866
3484 8888 Blank but applicable
28 Blank
1453-1458 Serum TIBC: SI (umol/L)
TIPSI 25802 012.36-0155.1
3484 888888 Blank but applicable
28 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1459-1462 Serum transferrin saturation (%) See note
PXP 25770 00.8-98.5
3516 8888 Blank but applicable
28 Blank
1463-1466 Serum ferritin (ng/mL)
FRP 13 0002 Below level of detection
26380 0003-3059
2893 8888 Blank but applicable
28 Blank
1467-1470 Serum ferritin: SI (ug/L)
FRPSI 13 0002 Below level of detection
26380 0003-3059
2893 8888 Blank but applicable
28 Blank
1471-1475 Serum folate (ng/mL) See note
FOP 1 000.1 Below level of detection
23704 000.4-00199
1937 88888 Blank but applicable
3672 Blank
1476-1480 Serum folate: SI (nmol/L)
FOPSI 1 000.2 Below level of detection
23704 000.9-450.9
1937 88888 Blank but applicable
3672 Blank
1481-1484 RBC folate (ng/mL) See note
RBP 23404 0007-1755
2238 8888 Blank but applicable
3672 Blank
1485-1490 RBC folate: SI (nmol/L)
RBPSI 23404 0015.9-3976.8
2238 888888 Blank but applicable
3672 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1491-1496 Serum vitamin B12 (pg/mL)
VBP 12024 000033-099999
722 888888 Blank but applicable
16568 Blank
1497-1504 Serum vitamin B12: SI (pmol/L)
VBPSI
12024 00024.35-73779.26
722 88888888 Blank but applicable
16568 Blank
1505-1508 Serum vitamin C (mg/dL) See note
VCP 20636 0000-4.72
2408 8888 Blank but applicable
6270 Blank
1509-1514 Serum vitamin C: SI (mmol/L)
VCPSI 20636 000000-000268
2408 888888 Blank but applicable
6270 Blank
1515-1518 Serum normalized calcium: SI (mmol/L) See note
ICPSI 16737 0.81-1.95
3022 8888 Blank but applicable
9555 Blank
1519-1522 Serum total calcium: SI (mmol/L)
CAPSI 4 1.06 Below level of detection
18490 1.57-3.29
1265 8888 Blank but applicable
9555 Blank
1523-1526 Serum selenium (ng/mL) See note
SEP 18597 0039-0622
1619 8888 Blank but applicable
9098 Blank
1527-1530 Serum selenium: SI (nmol/L)
SEPSI 18597 00.5-07.9
1619 8888 Blank but applicable
9098 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1531-1533 Serum vitamin A (ug/dL)
VAP 23274 002-259
2368 888 Blank but applicable
3672 Blank
1534-1537 Serum vitamin A: SI (umol/L)
VAPSI 23274 0.07-9.04
2368 8888 Blank but applicable
3672 Blank
1538-1542 Serum vitamin E (ug/dL) See note
VEP 23274 00028-09999
2368 88888 Blank but applicable
3672 Blank
1543-1548 Serum vitamin E: SI (umol/L)
VEPSI 23274 000.65-232.18
2368 888888 Blank but applicable
3672 Blank
1549-1551 Serum alpha carotene (ug/dL)
ACP 23274 000-202
2368 888 Blank but applicable
3672 Blank
1552-1555 Serum alpha carotene: SI (umol/L)
ACPSI 23274 0000-3.76
2368 8888 Blank but applicable
3672 Blank
1556-1559 Serum beta carotene (ug/dL) See note
BCP 5 0000 Below level of detection
23269 0001-0674
2368 8888 Blank but applicable
3672 Blank
1560-1564 Serum beta carotene: SI (umol/L)
BCPSI 5 00.00 Below level of detection
23269 00.02-12.56
2368 88888 Blank but applicable
3672 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1565-1567 Serum beta cryptoxanthin (ug/dL)
BXP 23272 000-144
2370 888 Blank but applicable
3672 Blank
1568-1571 Serum beta cryptoxanthin: SI (umol/L)
BXPSI 23272 0000-02.6
2370 8888 Blank but applicable
3672 Blank
1572-1574 Serum lutein/zeaxanthin (ug/dL) See note
LUP 3 000 Below level of detection
23271 001-478
2368 888 Blank but applicable
3672 Blank
1575-1578 Serum lutein/zeaxanthin: SI (umol/L)
LUPSI 3 0.00 Below level of detection
23271 0.02-08.4
2368 8888 Blank but applicable
3672 Blank
1579-1581 Serum lycopene (ug/dL) See note
LYP 25 000 Below level of detection
23249 001-124
2368 888 Blank but applicable
3672 Blank
1582-1585 Serum lycopene: SI (umol/L)
LYPSI 25 0.00 Below level of detection
23249 0.02-2.31
2368 8888 Blank but applicable
3672 Blank
1586-1588 Serum sum retinyl esters (ug/dL)
REP 23274 000-269
2368 888 Blank but applicable
3672 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1589-1592 Serum sum retinyl esters: SI (umol/L)
REPSI 23274 0000-9.39
2368 8888 Blank but applicable
3672 Blank
1593-1597 Serum cotinine (ng/mL) See note
COP 994 0.035 Below level of detection
9648 00.05-01470
2025 88888 Blank but applicable
16647 Blank
1598-1600 Serum cholesterol (mg/dL)
TCP 23561 059-702
2081 888 Blank but applicable
3672 Blank
1601-1605 Serum cholesterol: SI (mmol/L)
TCPSI 23561 01.53-18.15
2081 88888 Blank but applicable
3672 Blank
1606-1609 Serum triglycerides (mg/dL) See note
TGP 23515 0013-3616
2127 8888 Blank but applicable
3672 Blank
1610-1614 Serum triglycerides: SI (mmol/L)
TGPSI 23515 00.15-40.82
2127 88888 Blank but applicable
3672 Blank
1615-1617 Serum LDL cholesterol (mg/dL) See note
LCP 7891 020-380
2254 888 Blank but applicable
19169 Blank
1618-1621 Serum LDL cholesterol: SI (mmol/L)
LCPSI 7891 0.52-9.83
2254 8888 Blank but applicable
19169 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1622-1624 Serum HDL cholesterol (mg/dL)
HDP 23409 008-196
2233 888 Blank but applicable
3672 Blank
1625-1628 Serum HDL cholesterol: SI (mmol/L)
HDPSI 23409 0.21-5.07
2233 8888 Blank but applicable
3672 Blank
1629-1631 Serum apolipoprotein AI (mg/dL) See note
AAP 11432 059-300
1464 888 Blank but applicable
16418 Blank
1632-1635 Serum apolipoprotein AI: SI (g/L)
AAPSI 11432 0.59-0003
1464 8888 Blank but applicable
16418 Blank
1636-1638 Serum apolipoprotein B (mg/dL) See note
ABP 11483 040-260
1413 888 Blank but applicable
16418 Blank
1639-1642 Serum apolipoprotein B: SI (g/L)
ABPSI 11483 00.4-02.6
1413 8888 Blank but applicable
16418 Blank
1643-1645 Serum lipoprotein (a) (mg/dL)
LPP 12018 000-276
728 888 Blank but applicable
16568 Blank
1646-1649 Serum lipoprotein (a): SI (g/L)
LPPSI 12018 0000-2.76
728 8888 Blank but applicable
16568 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
GENERAL BIOCHEMISTRY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1650-1654 Serum follicle stimulating hormone: SI
FHPSI (IU/L)
6 000.1 Below level of detection
3116 000.2-00170
253 88888 Blank but applicable
25939 Blank
1655-1658 Serum luteinizing hormone: SI (IU/L)
LHPSI 2 00.1 Below level of detection
3118 00.2-67.1
255 8888 Blank but applicable
25939 Blank
1659-1662 Plasma fibrinogen (mg/dL)
FBP 9350 0019-0957
810 8888 Blank but applicable
19154 Blank
1663-1666 Plasma fibrinogen: SI (g/L)
FBPSI 9350 0.19-9.57
810 8888 Blank but applicable
19154 Blank
1667-1671 Serum C-reactive protein (mg/dL)
CRP 16218 00.21 Below level of detection
6249 000.3-025.2
3175 88888 Blank but applicable
3672 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
ANTIBODY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1672-1677 Serum tetanus antibody (U/mL)
TEP 19336 000000-074.67
5849 888888 Blank but applicable
4129 Blank
1678 Serum hepatitis A antibody
AHP (anti-HAV)
9872 1 Positive
11376 2 Negative
12 3 Borderline
1784 8 Blank but applicable
6270 Blank
1679 Serum hepatitis B core antibody See note
HBP (anti-HBc)
1368 1 Positive
19886 2 Negative
11 3 Borderline
1779 8 Blank but applicable
6270 Blank
1680-1681 Serum hepatitis B surface antibody See note
SSP (anti-HBs)
593 01 Positive
160 02 Negative
108 03 Borderline
340 11 > 10 mIU
155 22 < 10 mIU
1856 88 Blank but applicable
26102 Blank
1682 Serum hepatitis B surface antigen See note
SAP (HBsAg)
82 1 Positive
1292 2 Negative
1 3 Borderline
1837 8 Blank but applicable
26102 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
ANTIBODY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1683 Serum hepatitis C antibody
HCP (anti-HCV)
402 1 Positive
20796 2 Negative
43 4 Indeterminate
1803 8 Blank but applicable
6270 Blank
1684 Serum hepatitis D antibody See note
DHP (anti-HDV)
3 1 Positive
76 2 Negative
4 8 Blank but applicable
29231 Blank
1685 Serum herpes I antibody
H1P 9843 1 Positive
3205 2 Negative
50 3 Indeterminate
3184 8 Blank but applicable
13032 Blank
1686 Serum herpes II antibody
H2P 3532 1 Positive
9476 2 Negative
86 3 Indeterminate
3188 8 Blank but applicable
13032 Blank
1687-1691 Serum rubella antibody See note
RUP 21288 00000-72.91
2213 88888 Blank but applicable
5813 Blank
1692-1695 Serum rubella antibody (IU) See note
RUPUNIT 21288 0000-1224
2213 8888 Blank but applicable
5813 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
ANTIBODY TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1696-1700 Serum varicella antibody See note
VRP 21288 00000-29.64
2213 88888 Blank but applicable
5813 Blank
1701-1703 Serum toxoplasmosis antibody See note
TOP 17658 000-240
2558 888 Blank but applicable
9098 Blank
1704-1708 Serum rheumatoid factor antibody
RFP 5271 00000-40960
437 88888 Blank but applicable
23606 Blank
1709-1713 Serum latex antibody (IU/mL) See note
L1P 5524 00000-47.48
23790 Blank
1714 Serum helicobacter pylori antibody See note
HPP 848 1 Positive
1733 2 Negative
125 3 Equivocal
26608 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
BIOCHEMISTRY PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1715-1719 Serum sodium: SI (mmol/L)
NAPSI 18723 123.4-177.5
1493 88888 Blank but applicable
9098 Blank
1720-1723 Serum potassium: SI (mmol/L)
SKPSI 18723 2.51-6.94
1493 8888 Blank but applicable
9098 Blank
1724-1728 Serum chloride: SI (mmol/L)
CLPSI 18723 076.2-121.6
1493 88888 Blank but applicable
9098 Blank
1729-1730 Serum bicarbonate: SI (mmol/L)
C3PSI 18721 04-53
1495 88 Blank but applicable
9098 Blank
1731-1734 Serum total calcium (mg/dL)
SCP 18722 06.6-15.4
1494 8888 Blank but applicable
9098 Blank
1735-1739 Serum total calcium: SI (mmol/L)
SCPSI 18722 01.65-03.85
1494 88888 Blank but applicable
9098 Blank
1740-1743 Serum phosphorus (mg/dL)
PSP 18723 01.5-10.5
1493 8888 Blank but applicable
9098 Blank
1744-1748 Serum phosphorus: SI (mmol/L)
PSPSI 18723 0.484-03.39
1493 88888 Blank but applicable
9098 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
BIOCHEMISTRY PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1749-1752 Serum uric acid (mg/dL)
UAP 18723 00.2-15.9
1493 8888 Blank but applicable
9098 Blank
1753-1757 Serum uric acid: SI (umol/L)
UAPSI 18723 011.9-945.7
1493 88888 Blank but applicable
9098 Blank
1758-1760 Serum glucose (mg/dL) See note
SGP 18719 037-571
1497 888 Blank but applicable
9098 Blank
1761-1765 Serum glucose: SI (mmol/L)
SGPSI 18719 02.05-031.7
1497 88888 Blank but applicable
9098 Blank
1766-1768 Serum blood urea nitrogen (mg/dL)
BUP 18723 002-104
1493 888 Blank but applicable
9098 Blank
1769-1773 Serum blood urea nitrogen: SI (mmol/L)
BUPSI 18723 00.71-37.13
1493 88888 Blank but applicable
9098 Blank
1774-1777 Serum total bilirubin (mg/dL)
TBP 18723 0000-10.4
1493 8888 Blank but applicable
9098 Blank
1778-1783 Serum total bilirubin: SI (umol/L)
TBPSI 18723 000000-177.84
1493 888888 Blank but applicable
9098 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
BIOCHEMISTRY PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1784-1787 Serum creatinine (mg/dL)
CEP 18722 00.3-13.9
1494 8888 Blank but applicable
9098 Blank
1788-1793 Serum creatinine: SI (umol/L)
CEPSI 18722 0026.5-1228.8
1494 888888 Blank but applicable
9098 Blank
1794-1796 Serum iron (ug/dL) See note
SFP 14056 000-464
1493 888 Blank but applicable
13765 Blank
1797-1800 Serum iron: SI (umol/L)
SFPSI 14056 0000-83.1
1493 8888 Blank but applicable
13765 Blank
1801-1804 Serum cholesterol (mg/dL) See note
CHP 18721 0039-0748
1495 8888 Blank but applicable
9098 Blank
1805-1810 Serum cholesterol: SI (mmol/L)
CHPSI 18721 01.009-19.343
1495 888888 Blank but applicable
9098 Blank
1811-1814 Serum triglycerides (mg/dL) See note
TRP 14056 0003-3900
1493 8888 Blank but applicable
13765 Blank
1815-1820 Serum triglycerides: SI (mmol/L)
TRPSI 14056 00.034-44.031
1493 888888 Blank but applicable
13765 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
BIOCHEMISTRY PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1821-1823 Serum aspartate aminotransferase: SI
ASPSI (U/L)
18723 006-517
1493 888 Blank but applicable
9098 Blank
1824-1826 Serum alanine aminotransferase: SI
ATPSI (U/L)
18723 001-486
1493 888 Blank but applicable
9098 Blank
1827-1830 Serum gamma glutamyl transferase: SI See note
GGPSI (U/L)
14549 0001-1342
1495 8888 Blank but applicable
13270 Blank
1831-1834 Serum lactate dehydrogenase: SI
LDPSI (U/L)
18721 0029-0970
1495 8888 Blank but applicable
9098 Blank
1835-1838 Serum alkaline phosphatase: SI (U/L)
APPSI 18721 0017-0952
1495 8888 Blank but applicable
9098 Blank
1839-1842 Serum total protein (g/dL)
TPP 18723 04.6-10.4
1493 8888 Blank but applicable
9098 Blank
1843-1845 Serum total protein: SI (g/L)
TPPSI 18723 046-104
1493 888 Blank but applicable
9098 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
BIOCHEMISTRY PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1846-1848 Serum albumin (g/dL)
AMP 18723 0.9-6.1
1493 888 Blank but applicable
9098 Blank
1849-1851 Serum albumin: SI (g/L)
AMPSI 18723 009-061
1493 888 Blank but applicable
9098 Blank
1852-1854 Serum globulin (g/dL) See note
GBP 14056 1.5-6.6
1493 888 Blank but applicable
13765 Blank
1855-1857 Serum globulin: SI (g/L)
GBPSI 14056 015-066
1493 888 Blank but applicable
13765 Blank
1858-1860 Serum osmolality: SI (mmol/Kg) See note
OSPSI 14056 241-352
1493 888 Blank but applicable
13765 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DIABETES TESTING PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1861-1864 Glycated hemoglobin: (%) See note
GHP 23476 02.8-16.2
2166 8888 Blank but applicable
3672 Blank
1865 Glycated hemoglobin: test method See note
GHPMETH 13892 1 Diamat method (instrument 1)
4811 2 Diamat method (instrument 2)
2549 3 Diamat method (instrument 3)
2224 4 Affinity method
2166 8 Blank but applicable
3672 Blank
1866-1870 Plasma glucose - first venipuncture See note
G1P (mg/dL)
15877 035.4-642.6
674 88888 Blank but applicable
12763 Blank
1871-1876 Plasma glucose - first venipuncture: SI
G1PSI (mmol/L)
15877 01.965-35.671
674 888888 Blank but applicable
12763 Blank
1877-1878 Incomplete glucose test (OGTT) code See note
G1PCODE 2 20 Hemophiliac
11 21 Chemotherapy within 4 weeks
301 22 Diabetic on insulin
98 23 Refused venipuncture
42 24 Ill/faint during test
142 25 Venipuncture unsuccessful
12 26 Physician canceled test
187 27 Refused glucose challenge
368 99 All remaining reasons
28151 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DIABETES TESTING PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1879-1881 Minutes between glucose challenge and See note
G1PTIM1 second venipuncture
6640 086-178
855 888 Blank but applicable
21819 Blank
1882-1884 Minutes between first and second See note
G1PTIM2 venipuncture
6637 094-184
858 888 Blank but applicable
21819 Blank
1885-1889 Plasma glucose - second venipuncture See note
G2P (mg/dL)
6652 033.7-755.1
843 88888 Blank but applicable
21819 Blank
1890-1895 Plasma glucose - second venipuncture: SI
G2PSI (mmol/L)
6652 01.871-41.916
843 888888 Blank but applicable
21819 Blank
1896-1900 Serum C-peptide - first venipuncture See note
C1P (pmol/mL)
63 0.021 Below level of detection
15730 00.03-12.77
758 88888 Blank but applicable
12763 Blank
1901-1905 Serum C-peptide - first venipuncture: SI
C1PSI (nmol/L)
63 0.021 Below level of detection
15730 00.03-12.77
758 88888 Blank but applicable
12763 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DIABETES TESTING PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1906-1911 Serum C-peptide - second venipuncture See note
C2P (pmol/mL)
1 00.021 Below level of detection
3365 00.075-15.363
381 888888 Blank but applicable
25567 Blank
1912-1917 Serum C-peptide - second venipuncture:
C2PSI SI (nmol/L)
1 00.021 Below level of detection
3365 00.075-15.363
381 888888 Blank but applicable
25567 Blank
1918-1923 Serum insulin - first venipuncture See note
I1P (uU/mL)
65 001.76 Below level of detection
15689 002.51-002367
797 888888 Blank but applicable
12763 Blank
1924-1930 Serum insulin - first venipuncture: SI
I1PSI (pmol/L)
65 0010.56 Below level of detection
15689 0015.06-0014202
797 8888888 Blank but applicable
12763 Blank
1931 Serum insulin - first venipuncture: See note
I1P2PFLG test kit
2693 1 Kit 1
1906 2 Kit 2
11156 3 Kit 3
796 8 Blank but applicable
12763 Blank
1932-1937 Serum insulin - second venipuncture See note
I2P (uU/mL)
3378 0002.7-823.01
369 888888 Blank but applicable
25567 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
DIABETES TESTING PROFILE
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1938-1944 Serum insulin - second venipuncture: SI
I2PSI (pmol/L)
3378 00016.2-4938.06
369 8888888 Blank but applicable
25567 Blank
NHANES III Laboratory Data File
Whole Blood, Serum, Plasma, and Urine Data
------------------------------------------------------------------------
URINE TESTS
------------------------------------------------------------------------
Positions Item description
SAS name Counts and code Notes
------------------------------------------------------------------------
1945-1949 Urinary cadmium (ng/mL)
UDP 22321 00.01-16.65
749 88888 Blank but applicable
6244 Blank
1950-1955 Urinary cadmium: SI (nmol/L)
UDPSI 22321 000.09-148.14
749 888888 Blank but applicable
6244 Blank
1956-1960 Urinary creatinine (mg/dL) See note
URP 83 007.9 Below level of detection
22162 011.3-682.1
825 88888 Blank but applicable
6244 Blank
1961-1964 Urinary creatinine: SI (mmol/L)
URPSI 83 00.7 Below level of detection
22162 0001-60.3
825 8888 Blank but applicable
6244 Blank
1965-1970 Urinary albumin (ug/mL)
UBP 386 0000.4 Below level of detection
21859 0000.5-015700
825 888888 Blank but applicable
6244 Blank
1971-1977 Urinary iodine (ug/dL)
UIP 5 00000.1 Below level of detection
22085 00000.5-0019750
980 8888888 Blank but applicable
6244 Blank
DEMOGRAPHIC DATA: NOTES
Screener Questionnaire
DMPSTAT: Examination/interview status
This variable identifies the interview or examination status of all
persons selected for the NHANES III sample. Interviewed persons completed
preselected questions in specific sections of the Household Adult or
Youth Questionnaires. Mobile examination center (MEC)-examined persons
were interviewed and successfully completed at least one examination
component in the MEC. Home-examined persons were interviewed and
successfully completed at least one home examination component. The
home examination was an option for frail older adults, infants 2-11
months of age, and other adults who were unable to come to the MEC.
DMARETHN: Race-ethnicity
This key analytic variable, based on the NHANES III survey design, was
derived from many sources of data and is based on reported race and
ethnicity. The other category includes all Hispanics, regardless of
race, who were not Mexican-American and also includes all non-Hispanics
from racial groups other than white or black.
DMARACER: Race
This variable was obtained from two primary sources: the Screener and
the Family Questionnaires. Prior to the selection of the sample, race
(Black, White, Other) was self-reported or reported by proxy in the
Screener Questionnaire. During the administration of the Family
Questionnaire, race was self-reported or reported by the respondent of
the Family Questionnaire from five categories (Aleut, Eskimo, American
Indian, Asian or Pacific Islander, Black, White, Other). Responses from
the two sources were adjudicated, as necessary, to create a three level
variable (Black, White, Other).
DMAETHNR: Ethnicity
This variable was obtained from two primary sources: the Screener and
the Family Questionnaires. As part of both interviews, hand cards were
used to determine Mexican/Mexican-American or Other Latin
American/Spanish ancestry or national origin. Responses of non-Hispanic
ancestry or national origin were categorized as other. Responses from
the two interviews were adjudicated, as necessary, and this three
level variable was created.
HSAGEIR: Age (Screener Questionnaire)
Age was calculated using the birth date which was obtained from the
Screener Questionnaire. The variable HSAGEU provides the age unit
(months or years) for HSAGEIR. Ages of 90 years or greater were recoded
into a single category of 90+ years to help protect the confidentiality
of survey participants.
HSAITMOR: Age in months (Screener Questionnaire)
Age in months was calculated by computing number of months between the
Screener Questionnaire date and date of birth. This variable was
created for analyses where exact age at the interview may be needed.
HSAITMOR differs slightly from the age in years (HSAGEIR), the variable
most often used for analyses. Ages of 1080 months and older (90 years
and older) were recoded into a single category of 1080+ months to
protect the confidentiality of survey participants.
HSFSIZER: Family Size
Family size represents the total number of related persons living in a
household (single dwelling unit). All household members were rostered
by family during the Screener interview. Household members who were
related to the family reference person (knowledgeable household member
17 years or older who owned or rented the dwelling unit) by blood or
marriage were considered part of the family. Adopted children, foster-
and god-children were also included, if they were living in the dwelling
unit. However, family members who were away at college, or living
independently were not included. Other household members who were
unrelated to the reference person were considered members of separate
families. Families with 10 members or more were recoded into a single
response category of 10+ persons to help protect confidentiality. See
note for Household Size (HSHSIZER).
HSHSIZER: Household Size
Household size represents the total number of persons living in a single
dwelling unit, both related and unrelated. All permanent household
members were rostered according to their family as part the Screener
interview. This was done in order to obtain a complete list of all
persons living or staying in the dwelling unit, and to distinguish
household and family members. Households with 10 members or more were
recoded into a single response category of 10+ persons to help protect
confidentiality. See note for Family Size (HFHSIZER).
DMPCNTYR: County FIPS codes for United States counties with populations of
500,000 and more
These county FIPS codes identify large counties with populations of
500,000 and more that were sampled in the survey. Counties with
population less than 500,000 are not included to prevent identification
of these locations. See Appendix 1 for listing of codes.
DMPFIPSR: State FIPS codes for United States counties with populations of
500,000 and more
These state FIPS codes identify counties with populations of 500,000+
that were sampled in the survey. Counties with population less than
500,000 are not included to prevent identification of these locations.
See Appendix 1 for listing of codes.
DMPMETRO: Urbanization classification based on USDA Rural-Urban
continuum codes
These classifications are based on the USDA Rural-Urban codes (Butler and
Beale, 1993) that describe metro and nonmetro counties by degree of
urbanization and nearness to metro areas. The USDA codes were recoded
into two categories to prevent identification of counties that were
sampled in the survey.
DMPCREGN: Census region
The United States was divided into four broad geographic regions as
defined by the Bureau of Census. Because all states were not included in
the selected sample, regional estimates may not be representative for a
given region.
DMPPIR: Poverty income ratio (or poverty index)
The poverty income ratio (PIR) was computed as a ratio of two
components. The numerator was the midpoint of the observed family
income category in the Family Questionnaire variable:HFF19R. The
denominator was the poverty threshold, the age of the family reference
person, and the calender year in which the family was interviewed.
Poverty threshold values (in dollars) are produced annually by the
Census Bureau (Series P-60). These threshold values are based on
calendar years and adjusted for changes caused by inflation between
calendar years. Reports for each of the calendar years in the survey
(1988-94) were used in the calculation of PIR. For the years 1991 and
1994, data from preliminary reports were used. The poverty income ratio
allows income data to be analyzed in a comparable manner across the six
years of the survey and with previous NHANES.
Persons who reported having had no income and were assigned a zero value
for PIR. A substantial proportion of persons refused to report their
income or income category during the Family Questionnaire. Due to the
income nonresponse the potential for bias in PIR may be high. Users are
cautioned to examine potential nonresponse bias for PIR and
other income variables.
Survey Design Data
SDPPHASE: Phase of NHANES III survey
For operational purposes, 81 primary sampling units were divided into 89
survey locations (or stands) and randomly allocated to two three-year
phases. Phase 1 data were collected from October 1988 through October
1991 and Phase 2 data were collected from October 1991 through October
1994.
SDPSTRA6, SDPSTRA1, SDPSTRA2, and SDPPSU6, SDPPSU1, SDPPSU2: Pseudo strata
codes and pseudo PSU pair codes
Because NHANES III was based upon a complex sample design, the
assumptions of many statistical tests and routinely available
statistical programs are not met. For this reason, when estimates of
the variances of statistics are computed, the technique of estimation
must be based upon complex sampling theory. In order to provide users
with the capability of estimating the complex sample variances, 49
pseudo strata and a pair of Primary Sampling Unit (PSU) codes per
stratum were designed.
A software package, "SUDAAN- Software for the Statistical Analysis of
Correlated Data" (Shah, 1995), was developed by the Research Triangle
Institute to analyze complex sample design data like NHANES. SUDAAN
uses strata and PSU codes to conduct analysis with two PSU per stratum
design. Therefore, definition of pseudo strata and PSU provided in this
data file should be used to compute complex sample variances in
analyses. Other software available for estimation of complex sample
variance may also be used. For further discussion of methods of
variance estimation in NHANES III, see additional information on this
subject in Weighting and Estimation Methodology (U.S. DHHS, 1996) and
NHANES III Analytic and Reporting Guidelines (U.S. DHHS, 1996).
Sampling Weights
WTPFQX6, WTPFQX1, WTPFQX2: Total NHANES III and phase-specific final
interview weights
These sampling weights should be used only for items collected during
the household interviews. To compute final interview weights, final
basic weights were first adjusted for nonresponse to household
interview, then post-stratified to the unpublished Current Population
Survey 1990 (Phase 1) and 1993 (Phase 2) population control estimates of
the U.S. population adjusted for undercount. For details, see
Weighting and Estimation Methodology (U.S. DHHS, 1996) and NHANES III
Analytic and Reporting Guidelines (U.S. DHHS, 1996).
WTPFEX6, WTPFEX1, WTPFEX2: Total NHANES III and phase-specific final MEC
examination weights
These MEC sampling weights should be used for analysis of measurements
or interview items collected in the MEC. Persons who were not examined
in the MEC have a sampling weight of zero and should be excluded from
analyses. To compute final MEC examination weights, final interview
weights were first adjusted for nonresponse to MEC examinations, then
post-stratified to the unpublished Current Population Survey 1990
(Phase 1) and 1993 (Phase 2) population control estimates of the U.S.
population adjusted for undercount. For details, see Weighting and
Estimation Methodology(U.S. DHHS, 1996) and NHANES III Analytic and
Reporting Guidelines (U.S. DHHS, 1996).
WTPFHX6, WTPFHX1, WTPFHX2: Total NHANES III and phase-specific MEC+home
examination weights
These MEC+home sampling weights should be used for analysis of the
examination items where measurements or interview items were collected
in the MEC and home. Persons who were not examined in the MEC or home
have a sampling weight of zero and should be excluded from analyses. To
compute final MEC+home examination weights, final interview weights were
first adjusted for nonresponse to MEC and home examinations, then
post-stratified to unpublished Current Population Survey 1990 (Phase 1)
and 1993 (Phase 2) population control estimates of the U.S. population
adjusted for undercount. No separate sampling weights were computed for
home examinees. For details, see Weighting and Estimation Methodology
(U.S. DHHS, 1996) and NHANES III Analytic and Reporting Guidelines
(U.S. DHHS, 1996).
WTPFALG6, WTPFALG1, WTPFALG2: Total NHANES III and phase-specific allergy
examination subsample weights
These subsample weights are for analysis of allergy measurements.
Allergy skin reactivity tests were administered to all MEC-examined
persons aged 6-19 years and a random half-sample of the adults aged
20-59 years. Eligible MEC-examined persons who did not complete the
allergy tests have a sampling weight of zero and should be excluded from
the analyses. Final MEC examination weights were first adjusted for
selection of the half-sample among adults (20-59 years), and
post-stratified to the unpublished Current Population Survey 1990 (Phase
1) and 1993 (Phase 2) population control estimates of the U.S.
population adjusted for undercount in the final step. For details, see
Weighting and Estimation Methodology (U.S. DHHS, 1996) and NHANES III
Analytic and Reporting Guidelines (U.S. DHHS, 1996).
WTPFCNS6, WTPFCNS1, WTPFCNS2: Total NHANES III and phase-specific central
nervous system (CNS) examination subsample final weights
These subsample weights are for analysis of measurements from the
Central Nervous System (CNS) test. The CNS examination was administered
to a random half-sample of the adults aged 20-69 years. Eligible
MEC-examined persons who did not complete CNS testing have a sampling
weight of zero and should be excluded from the analyses. Final MEC
examination weights were first adjusted for selection of half sample
among adults (20-59 years), and post-stratified to unpublished Current
Population Survey 1990 (Phase 1) and 1993 (Phase 2) population control
estimates of the U.S. population adjusted for undercount in the final
step. For details, see Weighting and Estimation Methodology
(U.S. DHHS, 1996) and NHANES III Analytic and Reporting Guidelines
(U.S. DHHS, 1996).
WTPFSD6, WTPFSD1, WTPFSD2: Total NHANES III and phase-specific morning
session MEC examination subsample final weights
These subsample weights are for special analyses where fasting time may
be an important factor. They were computed for persons aged 12 years
and older who were scheduled and examined in the MEC morning session.
Sampled households in the survey were randomly assigned to one of two
groups -- morning session ("standard") or afternoon/evening session
("modified") assignments. All sample persons from a household received
the same session assignment and were requested to schedule examinations
for the assigned session. Fasting instructions varied by age and
session assignment (Plan and Operation of The Third National Health and
Nutrition Examination Survey, 1988-94 , U.S. DHHS, 1996). It should be
noted that actual fasting time may have differed from the instructed
fasting time and can be obtained from the variable PHPFAST in the NHANES
III Laboratory Data File. To compute these weights, final MEC examination
weights were first adjusted for the random half selection, then
adjusted for the non-response to assigned session, and finally,
post-stratified to the unpublished Current Population Survey 1990 and
1993 Population control estimates of the U.S. population adjusted for
undercount. Eligible MEC-examined persons who were assigned to the morning
session and examined in another session have a sampling weight of zero and
should be excluded in analyses. For details, see Weighting and Estimation
Methodology (U.S. DHHS, 1996) and NHANES III Analytic and Reporting
Guidelines (U.S. DHHS, 1996).
WTPFMD6, WTPFMD1, WTPFMD2: Total NHANES III and phase-specific
afternoon/evening session MEC examination subsample final
weights
These subsample weights are for special analyses where fasting time
might be an important factor. They were computed for MEC examined
persons aged 12 years and older who were scheduled and examined in the
afternoon or evening sessions. Sampled households in the survey were
randomly assigned to one of two groups -- morning session ("standard")
or afternoon/evening session ("modified") assignments. All sample
persons from a household received the same session assignment and were
requested to schedule examinations for the assigned session. Fasting
instruction varied by age and session assignments (Plan and Operation
of the Third National Health and Nutrition Examination Survey, 1988-94,
U.S. DHHS, 1996). It should be noted that actual fasting
time may have differed from the instructed fasting time and can be
obtained from the variable PHPFAST in the NHANES III Laboratory Data File.)
compute these weights, final MEC examination weights were first adjusted
for the random half selection, then adjusted for the nonresponse to
assigned session, and finally, post-stratified to the unpublished Current
Population Survey 1990 and 1993 population control estimates of the U.S.
population adjusted for undercount. Eligible MEC examined persons who were
assigned to the afternoon or evening sessions and examined in
another session have a sampling weight of zero and should be excluded in
analyses. For details, see Weighting and Estimation Methodology
(U.S.DHHS, 1996) and NHANES III Analytic and Reporting Guidelines
(U.S. DHHS, 1996).
WTPFHSD6, WTPFHSD1, WTPFHSD2: Total NHANES III and phase-specific morning
session MEC+home examination subsample final post
stratified weights
These subsample weights are for special analyses where fasting time may
be an important factor. They were computed for MEC+home examined
persons aged 12 years and older who were scheduled and examined in the
morning session. Sampled households in the survey were randomly
assigned to one of two groups -- morning session ("standard") or
afternoon/evening session ("modified") assignments. All sample persons
from a household received the same session assignment and were requested
to schedule examinations for the assigned session. Fasting instruction
varied by age and session assignments (Plan and Operations of the Third
National Health and Nutrition Examination Survey, 1988-94, U.S. DHHS,
1996). It should be noted that actual fasting time may have differed from
the instructed fasting time and can be obtained from the variable PHPFAST
in the NHANES III Laboratory Data File. To compute these weights, final
MEC+home examination weights were first adjusted for the random half
selection, then adjusted for the nonresponse to assigned session, and
finally, post-stratified to the unpublished Current Population Survey
1990 and 1993 population control estimates of the U.S. population adjusted
for undercount. Eligible MEC+home examined persons who were assigned to
the morning session and examined in another session have a sampling weight
of zero and should be excluded in analyses. For details, see Weighting and
Estimation Methodology (U.S. DHHS, 1996) and NHANES III Analytic and
Reporting Guidelines (U.S. DHHS, 1996).
WTPFHMD6, WTPFHMD1, WTPFHMD2: Total NHANES III and phase-specific afternoon/
evening MEC+home examination subsample final weights
These subsample weights are for special analyses where fasting time may
be an important factor. They were computed for MEC+home examined
persons aged 12 years and older who were scheduled and examined in the
afternoon or evening sessions. Sampled households in the survey were
randomly assigned to one of two groups -- morning session ("standard")
or afternoon/evening session ("modified") assignments. All sample
persons from a household received the same session assignment and were
requested to schedule examinations for the assigned session. Fasting
instruction varied by age and session assignments (Plan and Operation
of the Third National Health and Nutrition Examination Survey, U.S. DHHS,
1996). It should be noted that actual fasting time may have differed from
the instructed fasting time. The actual fasting time can be obtained from
the variable PHPFAST in the NHANES III Laboratory Data File. To compute
these weights, final MEC+home examination weights were first adjusted for
the random half selection, then adjusted for the nonresponse to assigned
session, and finally, post-stratified to the unpublished Current Population
Survey 1990 and 1993 population control estimates of the U.S. population
adjusted for undercount. Eligible MEC+home examined persons who were
assigned to the afternoon or evening sessions and examined in another
session have a sampling weight of zero and should be excluded in
analyses. For details, see Weighting and Estimation Methodology
(U.S. DHHS, 1996) and NHANES III Analytic and Reporting Guidelines
(U.S. DHHS, 1996).
WTPQRP1--WTPQRP52: Fay's BRR Replicate interview sample
To allow for alternative methods to estimate variance, 52 replicate
weights were computed using repeated sampling method where WESVAR or
other software that use repeated samples, can be used for estimating
variance. Fay's method (see Fay, 1990; Judkins, 1990) was used to draw
half samples and adjust sampling weights in each of the random half
samples. Sampling weights in one half sample were multiplied by the
factor k=1.7 and in the other half sample by k=0.3 using the Fay's
method. After this adjustment, sampling weights were further adjusted
for non-response and post-stratified using the same procedure as the
final full sample interview weights. These weights should be used only
for estimating variance of items from the household adult and youth
interviews. For details, see Weighting and Estimation Methodology
(U.S. DHHS, 1996) and NHANES III Analytic and Reporting Guidelines
(U.S. DHHS, 1996).
WTPXRP1--WTPXRP52: Fay's BRR Replicate weights for MEC- examined sample
To allow for alternative methods to estimate variance, 52 replicate
weights were computed using repeated sampling method where WESVAR or
other BRR type software can be used to estimate variance. Fay's method
(see Fay, 1990; Judkins, 1990) was used to draw half samples and adjust
sampling weights in each of the random half samples. Sampling weights
in one half sample were multiplied by the factor k=1.7 and in the other
half sample by k=0.3 using Fay's method. After this adjustment, weights
were further adjusted for nonresponse and were post-stratified using the
same procedure as the full sample final weights. These weights should
be used only for estimating variance of outcome measurements or
interview items from the MEC Examination. For details, see additional
information on this subject in Weighting and Estimation Methodology
(U.S. DHHS, 1996) and NHANES III Analytic and Reporting Guidelines (U.S.
DHHS, 1996).
Household Youth Questionnaire
HYAITMO: Age in months (Household Youth Interview)
Age in months was calculated by computing number of months between
Household Youth Interview date and the date of birth. It was created for
special analyses where exact age at the interview may be needed. This
computed age may be different from the self-reported age in HSAGEIR and
HSAGEU, or HSAITMOR. For most analyses, age reported in HSAGEIR (and
HSAGEU) should be used.
MEC Examination
MXPLANG: Language of MEC examination
This variables designates the language of conduct for the MEC examination.
questionnaires were designed to be implemented in a bilingual
(English/Spanish) format so that respondents could to be interviewed in
their preferred language. When it was necessary to conduct an interview
in a another language, a translator assisted the interviewer in
administering the questionnaires. These interviews were coded as other.
MXPSESSR: Examination session for MEC examinees
This variable designates the period during the day that the examination
occurred. To increase response rates and allow flexibility, examinations
were scheduled in three sessions: morning, afternoon and evening. On
occasion, more than one session was attended in order to complete the full
examination. In such a situation, the session was coded as the one when
most of the examinations were completed.
MXPAXTMR: Age in months at MEC examination
Age in total months was created for special analyses where exact age at the
examination may be needed (e.g., computation of growth charts). It was
calculated by computing number of months between examination date and the
date of birth. Some examinees may have had a birthday between household
interview and examination so that this computed age at examination may
differ slightly from the age reported in HSAGEIR (and HSAGEU), or HSAITMOR.
For most analyses age reported in HSAGEIR (and HSAGEU) should be used.
Ages of 1080 months and older (90 years and older) were recoded into a
single category of 1080+ months to protect the confidentiality of survey
participants.
Home Examination
HXPAXTMR: Age in months at home examination
Age in total months was created for special analyses where exact age at the
examination may be needed (e.g., computation of growth charts). It was
calculated by computing number of months between examination date and the
date of birth. Some examinees may have had a birthday between household
interview and examination so that this computed age at examination may
differ slightly from the age reported in HSAGEIR (and HSAGEU), or HSAITMOR.
For most analyses age reported in HSAGEIR (and HSAGEU) should be used.
Ages of 1080 months and older (90 years and older) were recoded into a
single category of 1080+ months to protect the confidentiality of survey
participants.
HXPSESSR: Examination session for home examinees
This variable designates the period during the day that the examination
occurred. To increase response rates and allow flexibility, examinations
were scheduled in three sessions: morning, afternoon and evening. On
occasion, more than one session was attended in order to complete the full
examination. In such a situation, the session was coded as the one when
most of the examinations were completed.
References
Butler MA, Beale CL. Rural-urban continuum codes for metro and nonmetro
counties, 1993. Agriculture and Rural Economy Division, Economic Research
Services, U.S. Department of Agriculture, Staff Report No. AGES-9425, 1993.
Fay RE. VPLX: Variance Estimates for Complex Surveys. In: Proceedings of the
Survey Research Methods section of the American Statistical Association, pp.
266-271, 1990.
Judkins DR. Fay's method for variance estimation. Journal of Official Statistics
6 (3):223-239. 1990.
U.S. Department of Health and Human Services(DHHS). National Center for Health
Statistics. NHANES III Reference Manuals and Reports (CD-ROM). Hyattsville,Md.:
Centers for Disease Control and Prevention, 1996. Available from National
Technical Information Service (NTIS), Springfield,Va. (Acrobat.PDF format;
includes access software: Adobe Systems Inc. Acrobat Reader 2.1)
Shah BV, Barnwell BG, Bieler GS. SUDAAN User's Manual: Software for Analysis of
Correlated Data, Release 6.04. Research Triangle Park, North Carolina. 1995.
Appendix 1. State and county FIPS codes for areas with populations
of 500,000 or more.
DMPFIPSR State DMPCNTYR County
4 Arizona 13 Maricopa
6 California 1 Alameda
6 California 19 Fresno
6 California 37 Los Angeles
6 California 59 Orange
6 California 71 San Bernardino
6 California 73 San Diego
6 California 85 Santa Clara
6 California 111 Ventura
12 Florida 25 Dade
12 Florida 31 Duval
12 Florida 99 Palm Beach
17 Illinois 31 Cook
25 Massachusetts 17 Middlesex
26 Michigan 125 Oakland
26 Michigan 163 Wayne
29 Missouri 189 St Louis
36 New York 29 Erie
36 New York 47 Kings
36 New York 59 Nassau
36 New York 61 New York
36 New York 81 Queens
36 New York 119 Westchester
39 Ohio 35 Cuyahoga
39 Ohio 61 Hamilton
42 Pennsylvania 3 Allegheny
42 Pennsylvania 45 Delaware
42 Pennsylvania 101 Philadelphia
44 Rhode Island 7 Providence
48 Texas 29 Bexar
48 Texas 113 Dallas
48 Texas 141 El Paso
48 Texas 201 Harris
48 Texas 439 Tarrant
53 Washington 33 King
LABORATORY DATA: NOTES
AAP: Serum apolipoprotein AI
Apolipoprotein AI and apolipoprotein B results were measured only
during 1988-1991. Three different methods were used at different times
to measure apolipoprotein AI and apolipoprotein B. These were radial
immunodiffusion (RID), rate immunonephelometry (INA), and the World
Health Organization -International Federation of Clinical Chemistry
(WHO-IFCC) method (Bachorik, 1994; Marcovina, 1991; Albers, 1989).
Results using the RID and INA methods were adjusted to the WHO-IFCC
method.
ABP: Serum apolipoprotein B
See note for AAP.
ANP: Anisocytosis
Microscopic examination (manual differential) of the peripheral blood
spread on a glass slide utilized a stained blood film to perform a
differential leukocyte count, evaluate red cell morphology, and
estimate number of platelets. Manual differential variables include
segmented neutrophils, lymphocytes, monocytes, eosinophils, basophils,
blasts, promyelocytes, metamyelocytes, myelocytes, bands, atypical
lymphocytes, anisocytosis, basophilic stippling, hypochromia,
poikilocytosis, polychromatophilia, macrocytosis, microcytosis, sickle
cells, spherocytosis, target cells, toxic granulation, and vacuolated
cells (GRPDIF, LMPDIF, MOPDIF, EOP, BAP, BOP, BLP, PRP, MEP, MLP,
BAP, LAP, ANP, BSP, HZP, PKP, POP, MRP, MIP, SIP, SHP, TTP, TXP, and
VUP).
In NHANES III, a manual differential was performed on a special
subsample of examinees aged one year and older. This manual
differential was used for internal quality control purposes and to
confirm abnormal hematology results. This subsample was defined as a
random 10-percent sample of all examined persons plus all examinees
who had a predetermined high or low value for one or more of the
following hematologic assessments: white blood cell count (WBC), red
blood cell count (RBC), hemoglobin, hematocrit, mean cell volume (MCV),
mean cell hemoglobin (MCH), mean cell hemoglobin concentration (MCHC),
red blood cell distribution width (RDW), platelet count, mean platelet
volume (MPV), lymphocyte percentage, mononuclear percentage, or
granulocyte percentage. A table of predetermined high and low values
for WBC, RBC, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, platelet
count, MPV, lymphocyte percentage, mononuclear percentage, and
granulocyte percentage is located in the Manual for Medical Technicians
(U.S. DHHS, pp. 5-54 and 5-55, 1996).
BAP: Band cells
See note for ANP.
BCP: Serum beta carotene
The lower limit of detection (LOD) for beta carotene was 0.67 ug/dL.
Using the LOD coding formula (detection limit divided by the square
root of two), the calculated value to indicate that the serum beta
carotene results were below the level of detection would be 0.48. After
rounding, the value of 0 (zero) was placed in the results field to
indicate that the serum beta carotene was below 0.67 ug/dL.
BLP: Blast cells
See note for ANP.
BOP: Basophil cells
See note for ANP.
BSP: Basophilic stippling
See note for ANP.
C1P: Serum C-peptide (first venipuncture)
The specimen for this assay was obtained at the time of the initial
venipuncture. This result is available for all six years of the
survey.
Examinees aged 40-74 years who used insulin were excluded from the
OGTT. A first venipuncture was obtained, but the glucose challenge and
second venipuncture were canceled. In these instances, the variables
G1P, C1P and I1P have a value, but the results G2P, C2P and I2P from the
second venipuncture are blank-filled to indicate a medical exclusion.
C2P: Serum C-peptide (second venipuncture)
Post-glucose challenge levels of C-peptide and insulin for examinees
who had an OGTT were measured only during 1991-1994.
CHP: Serum cholesterol
This value was obtained from the standard battery of biochemical
assessments. Use of the laboratory test result from the reference
method (TCP), rather than the CHP value, is generally recommended.
For most analyses of serum cholesterol, the appropriate variable to use
will be TCP. The value from the biochemistry profile (CHP) should not
be used routinely. Consult the Laboratory Procedures Used for NHANES
III (U.S. DHHS, 1996) for the details.
COP: Serum cotinine
Only cotinine results from 1988-1991 are included in this field.
DHP: Serum hepatitis D antibody
Hepatitis B virus testing scheme: From 1988-1991, all sera were
tested for the core antibody to hepatitis B virus (anti-HBc). If this
test was positive, the sera were tested for the hepatitis B surface
antigen (HBsAg) and hepatitis B surface antibody (anti-HBs). If the
HbsAg test was positive and the anti-HBs test was <10 mIU, then the
antibody to hepatitis D virus (anti-HDV) test was performed. If the
HbsAg test was negative and the anti-HBs test was <10 mIU, then the
anti-HBc test was repeated for confirmation.
In June 1993, all sera were tested for both anti-HBc and anti-HBs.
Sera testing positive for anti-HBc were tested further for HBsAg, and
positive HBsAg samples were tested for anti-HDV.
EOP: Eosinophil cells
See note for ANP.
FEP: Serum iron
Laboratory methods differed between NHANES III and previous surveys.
Therefore, results may not be comparable between surveys. Consult the
Laboratory Procedures Used for NHANES III (U.S. DHHS, 1996).
FOP: Serum folate
Laboratory methods differed between NHANES III and previous surveys.
Therefore, results may not be comparable between surveys. Consult the
Laboratory Procedures Used for NHANES III (U.S. DHHS, 1996).
G1P: Plasma glucose (first venipuncture)
Plasma glucose was measured using the reference method on examinees
aged 20 years and older. Consult the Laboratory Procedures Used for
NHANES III (U.S. DHHS, 1996) for details.
During NHANES III, OGTT testing was conducted on MEC examinees aged
40-74 years. A random assignment was made prior to conducting the OGGT
to determine who should receive a morning examination (NCHS, 1994; U.S.
DHHS, 1996). As a result, approximately half of the OGGT examinees
received the morning OGTT after an overnight fast. This subsample
most closely conformed to the World Health Organization (WHO) criteria
for OGTT testing to identify diabetes (WHO, 1995). Therefore, this
morning subsample is the NHANES III subsample that should be used to
estimate the prevalence of diabetes and impaired glucose tolerance.
People who reported a medical history of diabetes but who were not using
insulin therapy were asked to conform to the fasting instructions for
their examination session and were eligible for an OGTT if the age
criteria were satisfied. The morning sample weights (WTPFHSD6) for
total NHANES III weights for the morning OGTT subsample should be used
when weighting these data to generate national estimates. Data from the
afternoon and evening OGTTs do not conform to the WHO protocol for
diagnosing diabetes or IGT and should not be used for these purposes.
If an examinee was given an OGTT during an examination session other
than the session assigned, that examinee's sample weight for the
assigned session will be zero. For example, if an examinee was
selected for a morning OGTT but was tested in the afternoon, the
examinee's morning sample weight for the OGTT will be zero.
G1PCODE: Reasons for an incomplete glucose tolerance test
The reason for which an examinee aged 40-74 years did not complete the
OGTT was entered in this field. This field either will contain an
incomplete OGTT code or will be blank. Examinees who responded
affirmatively to the hemophilia question (code 20) or who received
chemotherapy within the past four weeks (code 21) were excluded from
venipuncture. Examinees who reported on their examination day that
they used insulin therapy (code 22) were excluded from the OGTT. Codes
23-27 were recoded from comments and notations on the questionnaires
and may not include complete data on these reasons.
G1PTIM1: Interval between glucose drink and second venipuncture in minutes
If an examinee was aged 40-74 years and received the OGTT, the time
that the glucose drink was consumed and the time of the second
venipuncture were recorded. This variable contains the calculated time
difference between the glucose drink consumption and the second
venipuncture.
G1PTIM2: Interval between first and second venipuncture in minutes
If an examinee was aged 40-74 years and received the OGTT, two timed
venipunctures were performed. This variable contains the calculated
time difference between the first and second venipunctures.
G2P: Plasma glucose (second venipuncture)
See notes for C1P and G1P.
GBP: Serum globulin
Globulin results were added to the protocol after NHANES III began.
This result field was blank-filled for examinees who were examined
prior to the start of testing.
GGPSI: Serum gamma glutamyl transferase
Gamma glutamyl transferase results were added to the protocol after
NHANES III began. This result field was blank-filled for examinees
who were examined prior to the start of testing.
GHP: Glycated hemoglobin (HbA1c)
Glycohemoglobin measurements for NHANES III were performed by the
Diabetes Diagnostic Laboratory at the University of Missouri --
Columbia using the Diamat Analyzer System (Bio-Rad Laboratories,
Hercules, CA). This ion-exchange HPLC system measures HbA1c (a specific
glycohemoglobin) and has demonstrated excellent, long-term precision
(interassay CV's 2.0). It was standardized to the reference method
that was used for the Diabetes Control and Complications Trial (DCCT).
Variant hemoglobins, including hemoglobin C, D, F, and elevated HbF,
can interfere with HbA1c measurement by the Diamat HPLC. Hemoglobin S
in its heterozygous state does not interfere with this assay. Although
interferences usually can be detected by an abnormal Diamat
chromatogram, HbA1c results for these specimens were not considered
valid. Therefore, samples containing hemoglobin variants or elevated
HbF or samples that produce chromatograms indicating hemoglobin
degradation were analyzed by an alternate method that used affinity
chromatography to separate glycohemoglobin. Affinity chromatographic
methods were not affected by the presence of hemoglobin variants and
were less sensitive to hemoglobin degradation due to improper sample
handling. The affinity method used also was standardized to the DCCT
reference method. Reasons for using the affinity method for an
examinee's test included an extra peak on the chromatogram, hemoglobin
C, elevated hemoglobin F, or other abnormal hemoglobin.
GHPMETH: Glycated hemoglobin method
See note for GHP.
GRP: Granulocyte number
Consult the Manual for Medical Technicians for the Coulter granulocyte
number, lymphocyte number, mononuclear number, white blood cell count,
red blood cell count, and platelet count units (U.S. DHHS, 1996).
GRPDIF: Segmented neutrophil cells
See note for ANP.
HBP: Serum hepatitis B core antibody
See note for DHP.
HGP: Hemoglobin
In NHANES I, NHANES II, and HHANES, determinations of red and white
blood cell counts were made using a semiautomated cell counter
(Coulter model FN). Determinations of hemoglobin concentration (Hb)
were made using a Coulter hemoglobinometer, and determinations of packed
cell volume (PCV) were made using the microhematocrit centrifuge method.
The hematologic indices MCH, MCHC, and MCV were calculated as follows:
MCH = Hb/RBC
MCHC = Hb/PCV
MCV = PCV/RBC
In NHANES III, these hematologic parameters were determined by using a
fully automated Coulter S+JR hematology analyzer. These analyzers
measured the mean (red) cell volume (MCV) directly, utilizing a
process of continuous integration of pulse heights divided by the pulse
number; PCV values were calculated through the multiplication of MCV and
RBC.
Although it has been shown that identified errors in the
microhematocrit method caused by plasma trapping and red cell
dehydration approximately compensate each other (Bull, 1990), packing
errors can occur in macrocytic anemia and can be considerable in sickle
cell anemia, spherocytosis, and thalassemias (NCCLS, 1993). Therefore,
individual values for MCV, PCV ("hematocrit"), and MCHC from NHANES III
cannot be compared directly to values from the previous NHANES.
HPP: Serum Helicobacter pylori antibody
H. pylori antibody testing was performed on surplus sera from children
and adolescents aged 6-19 years. This result field was blank-filled
for examinees aged 6-19 years for whom surplus specimens were not
available for testing. Due to variability in the laboratory test
(Pylori Stat, Whittaker Bioproducts, Inc.), 50 percent of the assays
were repeated randomly. There was a seven-percent error rate in which
the first result (HPP) did not match the repeat result (HPQ). The
original result was kept if the controls on the ELISA plate were within
the acceptable range. Testing on adults will be performed at a later
date using the same assay.
HTP: Hematocrit
See note for HGP.
HZP: Hypochromia
See note for ANP.
I1P: Serum insulin (first venipuncture)
This is the adjusted insulin value for examinees. Most of the insulin
values in NHANES III (1988-1991) were adjusted because the
manufacturer of the laboratory testing kits changed during that period.
An indicator of the kit number is located in the I1P2PFLG field (i.e., 1
= Kit 1, 2 = Kit 2, and 3 = Kit 3). All insulin values from Kit 1 and
Kit 2 assays were adjusted linearly to match the Kit 3 numbers. Further
information on this adjustment procedure is available in the Laboratory
Procedures Used for NHANES III (U.S. DHHS, 1996).
The equations used to adjust the data were:
Kit 3 = 0.787 (Kit 1) + 0.832 Equation 1
Kit 3 = 0.597 (Kit 2) + 1.746 Equation 2
The following steps were used to make the adjustment:
1. Equation 1 was applied to group 1 (Kit 1) data
2. Equation 2 was applied to group 2 (Kit 2) data
3. Group 3 data (Kit 3) were left unchanged.
The time periods for the insulin kits were as follows:
Group Assay Period Assay Method
1 10/88-01/05/90 Kit 1
2 01/06/90-09/06/90 Kit 2
3 11/01/90-end of study Kit 3
See note for C1P.
I1P2PFLG: Insulin adjustment flag
This field shows which kit was used for the original insulin
measurement.
I2P: Serum insulin (second venipuncture)
See notes for C1P, C2P and I1P.
ICPSI: Serum normalized calcium
This variable contains the normalized calcium value derived from
adjusting the measured ionized calcium for pH. Consult the Laboratory
Procedures Used for NHANES III (U.S. DHHS, 1996) for details.
L1P: Serum latex antibody
Latex antibody testing was performed on surplus sera from persons ages
17-60 years who were examined in phase 1 (1988-
91). This result field was blank-filled for examinees ages 17-60 years
for whom surplus specimens were not available for testing.
LAP: Atypical lymphocyte cells
See note for ANP.
LCP: Serum LDL cholesterol calculation
The value for LDL was calculated by the Friedewald equation as
follows:
LDL = total cholesterol - high density cholesterol - triglyceride/5.
Because the equation is not valid when serum triglyceride values
exceed 400 mg/dL, the LDL is missing when serum triglyceride (TGP)
exceeds 400 mg/dL.
Serum LDL was calculated on examinees who were instructed to fast
(ages 12 and older) and who did fast at least nine hours, were examined
in the morning, and were randomly assigned to the morning fasting sample
(WTPFHSD6 > 0). Therefore, LDL would be blank if examinees were aged
less than 12 years, fasted fewer than nine hours, were examined in an
afternoon or evening session, or were not randomly assigned to the
morning session. For the purpose of this calculation, the number of
hours fasted was rounded to the nearest whole integer.
For more information regarding this equation, refer to the Laboratory
Procedures Used for NHANES III (U.S. DHHS, 1996).
LMP: Lymphocyte number
See note for GRP.
LMPDIF: Lymphocyte cells
See note for ANP.
LUP: Serum lutein/zeaxanthin
The lower limit of detection (LOD) for lutein/zeaxanthin was 0.43
ug/dL. Using the LOD coding formula (detection limit divided by the
square root of two), the calculated value indicating that the serum
lycopene results were below the level of detection would be 0.30. After
rounding, the value of 0 (zero) was placed in the results field to
indicate that the serum lutein/zeaxanthin was below 0.43 ug/dL.
LYP: Serum lycopene
The lower limit of detection (LOD) for lycopene was 0.63 ug/dL. Using
the LOD coding formula (detection limit divided by the square root of
two), the calculated value indicating that the serum lycopene results
were below the level of detection would be 0.44. After rounding, the
value of 0 (zero) was placed in the results field to indicate that the
serum lycopene was below 0.63 ug/dL.
MCPSI: Mean cell hemoglobin
See note for HGP.
MEP: Metamyelocyte cells
See note for ANP.
MHP: Mean cell hemoglobin concentration
See note for HGP.
MIP: Microcytosis
See note for ANP.
MLP: Myelocyte cells
See note for ANP.
MOP: Mononuclear number
See note for GRP.
MOPDIF: Monocyte cells
See note for ANP.
MRP: Macrocytosis
See note for ANP.
MVPSI: Mean cell volume
See note for HGP.
OSPSI: Serum osmolality
Results for osmolality were added to the protocol after NHANES III
began. This result field is blank-filled for examinees who were
examined prior to the start of testing.
PHPBEST: Time of venipuncture
The time of venipuncture is expressed using the 24-hour clock system
(military time) in which 01:00 corresponds to 1:00 a.m., 12:00
corresponds to 12 noon, 13:00 corresponds to 1:00 p.m., and 00:00
corresponds to 12 midnight.
PHPCHM2: Within the past four weeks have you received any cancer
chemotherapy treatment?
All examinees who indicated at the time of venipuncture that they had
received cancer chemotherapy treatment in the past two weeks (later
this was changed to four weeks) were excluded from venipuncture. For
these examinees, results fields for blood-based analyses are
blank-filled.
PHPFAST: Calculated fasting time in hours
The fasting time was calculated using the time of venipuncture and the
time the examinee last ate or drank (other than water). This was
determined using the snack/drink time and the corresponding day
variables. Fasting time is the elapsed interval between the time the
examinee last ate or drank and the time of venipuncture.
The following variables were used to calculate this variable:
PHPSNTI, PHPSNDA, PHPDRIN, PHPDRTI, PHPDRDA, and PHPBEST. If the
examinee drank only water since he/she last ate (PHPDRIN = 2), then the
time and day the examinee last ate (PHPSNTI and PHPSNDA) were subtracted
from the time and day of the venipuncture (PHPBEST). The difference was
the number of hours between the time the examinee last ate and the time
of the venipuncture.
If the examinee drank anything other than water (PHPDRIN = 1), then
the time and day the examinee last drank (PHPDRTI and PHPDRDA) were
subtracted from the time and day of the venipuncture (PHPBEST). The
difference was the number of hours between the time the examinee last
drank and the time of the venipuncture.
PHPHEMO: Do you have hemophilia?
All examinees who indicated at the time of venipuncture that they had
hemophilia, a hereditary blood-clotting disorder, were excluded from
the venipuncture. Results for blood analyses were blank-filled.
PHPINSU: Are you currently taking insulin?
See note for G1P and G1PCODE.
PHPLANG: Language of the venipuncture screening questionnaire
Both English and Spanish versions of the venipuncture screening
questionnaire were used. The language used depended on the preference
of the examinee. Translators, either hired or friends/family members,
were available for examinees who spoke neither Spanish nor English.
PKP: Poikilocytosis
See note for ANP.
PLP: Platelet count
See note for GRP.
POP: Polychromatophilia
See note for ANP.
PRP: Promyelocyte cells
See note for ANP.
PXP: Serum transferrin saturation
This value was calculated as (FEP/ TIP) * 100.
RBP: RBC folate
See note for FOP.
RCP: Red blood cell count
See notes for HGP and GRP.
RUP: Serum rubella antibody
Rubella antibody data are reported both as an optical density index
and in International Units. The index was calculated by subtracting the
absorbance of the control well from the absorbance of the antigen well
(AG-NS) and dividing the difference by the cut-off value. The cut-off
value was calculated as the mean AG-NS value of duplicate 10 IU
standards. The equation used was:
O.D. index = (AG-NS)/Cut-off value
An O.D. index greater than or equal to one indicates the presence of
antibody.
RUPUNIT: Serum rubella antibody (IU)
Rubella antibody data are reported both as an optical density index
and in International Units. International Units were calculated based
on a standard curve using a regression analysis of duplicate AG-NS
values of 10, 40, & 100 IU standards and their squares. An
International Unit value greater than or equal to 10 indicates the
presence of antibody.
SAP: Serum hepatitis B surface antigen
See note for HBP.
SEP: Serum selenium
Selenium values were measured on two Perkin-Elmer graphite furnace
atomic absorption spectrophotometers (model 3030 and model 5100)
during the six-year study. Based on a comparability study using linear
models, the results generated using the Model 5100 instrument (from
12/07/90 to 1/13/95) were on average 4.3 percent higher than those from
the Model 3030 instrument (used from 10/1/88 to 12/06/90). Since the
Model 5100 represented more precise measurements, the model 3030 data
were adjusted to make them comparable to the Model 5100. Perkin-Elmer
Model 5100 Zeeman-corrected graphite furnace atomic absorption
spectrophotometer testing began on 12/07/90. All selenium values
measured prior to 12/07/90 were adjusted to the AA5100 values. The
formula used was:
New value = 16.795 + 0.902 * original value.
SFP: Serum iron
This value was obtained from the standard battery of biochemical
assessments. Use of the laboratory test result from the reference
method (FEP), rather than the SFP value, is generally recommended.
For most analyses of serum iron, the appropriate variable to use will be
FEP. The value from the biochemistry profile (SFP) should not be used
routinely. Consult the Laboratory Procedures Used for NHANES III
(U.S. DHHS, 1996) for details. Laboratory test results for SFP were
added to the protocol after NHANES III began. This result field was
blank-filled for examinees who were examined prior to the start of
testing.
SGP: Serum glucose
This value was obtained from the standard battery of biochemical
assessments. Use of the laboratory test result for plasma glucose
from the reference method (G1P), rather than the SGP value, is generally
recommended. For most analyses, the appropriate variable to use will
be G1P. The value from the biochemistry profile (SGP) should not be
used routinely. Consult the Laboratory Procedures Used for NHANES III
(U.S. DHHS, 1996) for details.
SHP: Spherocytosis
See note for ANP.
SIP: Sickle cells
See note for ANP.
SSP: Serum hepatitis B surface antibody
See note for HBP.
TGP: Serum triglycerides
Serum triglyceride levels were measured regardless of the examinee's
fasting status. Mean serum triglycerides and the distribution of
serum triglycerides should be estimated only on examinees who did fast
at least nine hours, were examined in the morning, and were randomly
assigned to the morning fasting sample (WTPFHSD6 > 0). For the
purpose of this calculation, the number of hours fasted was rounded to
the nearest whole integer. Consult the Laboratory Procedures Used for
NHANES III (U.S. DHHS, 1996) for details.
TOP: Serum toxoplasmosis antibody
The presence and quantity of antibody to Toxoplasma gondii in the test
sample were determined by comparing the optical density of the test
sample to a standard curve. A standard curve was constructed using
optical density readings from positive control sera obtained from a
kit; these readings were calibrated to WHO Toxo 60 serum and read as
International Units (IU/mL). Those test samples exhibiting titer
below 7 IU/mL indicated a non-significant level of antibody according to
this technique; thus, they were considered to be negative, indicating no
infection. Those test samples with results greater than 6 IU/mL were
considered to be positive, indicating infection at some undetermined
time.
TRP: Serum triglycerides
This value was obtained from the standard battery of biochemical
assessments. Use of the laboratory test result from the reference
method (TGP), rather than the TRP value, is generally recommended.
For most analyses, the appropriate variable to use is TGP. The value
from the biochemistry profile (TRP) should not be used routinely.
Consult the Laboratory Procedures Used for NHANES III (U.S. DHHS, 1996)
for details. Results for TRP were added to the protocol after NHANES
III began. This result field was blank-filled for examinees who were
examined prior to the start of testing.
TTP: Target cells
See note for ANP.
TXP: Toxic granulation
See note for ANP.
URP: Urinary creatinine
Although the laboratory method detection limit for urinary creatinine
is 1 mg/dL, all values below 10 mg/dL were considered "statistically
suspect" and were coded as "below level of detection".
VCP: Serum vitamin C
For NHANES III, serum concentrations of vitamin C were measured using
a total vitamin C, fully reduced method using high-performance liquid
chromatography with electrochemical detection (HPLC-EC) analysis.
This method differed from the 2,4-dinitrophenyl hydrazine colorimetric
method used in the NHANES II study. A comparison study of the two
methods was carried out. Linear regression analysis, by an error in
both variables' technique, was used to compare the results obtained by
the two methods; values for slope, intercept, and correlation
coefficient were 0.881, 0.036, and 0.927, respectively, for 138
singlet analyses.
Serum concentrations obtained by HPLC-EC were lower than those
obtained by the 2,4-DNPH method. This difference was expected due to
the increased specificity of the HPLC method. Unlike colorimetric
methods, HPLC separates uric acid and other potential interferers from
ascorbate, thereby increasing accuracy and specificity. The 2,4-DNPH
method also measured endogenous diketogulonate, the product of the
irreversible oxidation of dehydroascorbic acid. This species was not
measured by most HPLC methods and generally was not included in total
vitamin C measurements since it has no vitamin C activity. Because the
laboratory method differed between NHANES III and NHANES II, the results
from the two surveys are not comparable.
Blocks of vitamin C data are missing due to an inadvertent misdilution
of the ascorbic acid-serum ratio.
VEP: Serum vitamin E
The vitamin E value of 9999 was confirmed.
VRP: Serum varicella antibody
Varicella antibody data were reported as an optical density index.
See note RUP for the index calculation. The equation used was:
O.D. index = (AG-NS)/Cut-off value
The cut-off value was 0.1. An O.D. index equal to or greater than one
indicates the presence of antibody.
VUP: Vacuolated cells
See note for ANP.
WCP: White blood cell count
See note for HGP and GRP.
Appendix 1. Blood and Urine Assessments by Specimen Type and Age Group
AGE GROUP
1-3 years 4-5 years 6-11 years
Whole blood
CBC (1)(5) CBC (1) (5) CBC (1) (5)
Differential smear Differential Differential
smear smear
Lead (5) Lead (5) Lead (5)
Protoporphyrin (5) Protoporphyrin (5) Protoporphyrin (5)
RBC folate RBC folate
Glycated Glycated
hemoglobin (5) hemoglobin (5)
Serum
Iron (5) Iron (5) Iron (5)
TIBC (5) TIBC (5) TIBC (5)
Ferritin (5) Ferritin (5) Ferritin (5)
Folate (5) Folate (5)
Apolipoprotein Apolipoprotein
AI(4)(5) AI(4)(5)
Apolipoprotein Apolipoprotein
B(4)(5) B(4)(5)
Cholesterol (5) Cholesterol (5)
HDL/LDL (5) HDL/LDL (5)
Triglycerides (5) Triglycerides (5)
Lp(a)(2)(5) Lp(a)(2)(5)
Cotinine (4) Cotinine (4)
C-reactive C-reactive
protein (5) protein (5)
Vitamin A (5) Vitamin A (5)
Carotenes (5) Carotenes (5)
Retinyl esters (5) Retinyl esters (5)
Vitamin E (5) Vitamin E (5)
Vitamin B12 (2) Vitamin B12 (2)
Helicobacter pylori (4)
Tetanus Tetanus
Vitamin C
Hepatitis A
Appendix 1. Blood and Urine Assessments by Specimen Type and Age Group
(continued)
AGE GROUP
1-3 years 4-5 years 6-11 years
Serum (continued)
Hepatitis B/delta
Hepatitis C
Hepatitis E
Rubella (5)
Varicella (5)
Urine
Cadmium
Creatinine
Albumin
Iodine
Appendix 1. Blood and Urine Assessments by Specimen Type and Age Group
(continued)
AGE GROUP
12-19 years 20 years and older
Whole blood
CBC (1)(5) CBC (1)(5)
Differential smear Differential smear
Lead (5) Lead (5)
Protoporphyrin (5) Protoporphyrin (5)
RBC folate
Glycated hemoglobin (5) Glycated hemoglobin (5)
Serum
Iron (5) Iron (5)
TIBC (5) TIBC (5)
Ferritin (5) Ferritin (5)
Folate (5) Folate (5)
Apolipoprotein AI(4)(5) Apolipoprotein AI(4)(5)
Apolipoprotein B(4)(5) Apolipoprotein B(4)(5)
Cholesterol (5) Cholesterol (5)
HDL/LDL (5) HDL/LDL (5)
Triglycerides (5) Triglycerides (5)
Lp(a)(2)(5) Lp(a)(2)(5)
Cotinine (4) Cotinine (4)
C-reactive protein (5) C-reactive protein (5)
Rheumatoid factor (60+)
Vitamin A (5) Vitamin A (5)
Carotenes (5) Carotenes (5)
Retinyl esters (5) Retinyl esters (5)
Vitamin E (5) Vitamin E (5)
Vitamin B12 (2) Vitamin B12 (2)
Helicobacter pylori (4)
Tetanus Tetanus
Vitamin C Vitamin C
Hepatitis A Hepatitis A
Hepatitis B/delta Hepatitis B/delta
Hepatitis C Hepatitis C
Hepatitis E Hepatitis E
Rubella (5) Rubella (5)
Varicella (5) Varicella (5)
Appendix 1. Blood and Urine Assessments by Specimen Type and Age Group
(continued)
AGE GROUP
12-19 years 20 years and older
Serum
Diphtheria Diptheria
Herpes simplex I and II Herpes simplex I and II
HIV I (ages 18+)(3)(5) HIV I (ages 18+)(3)(5)
Toxoplasmosis (5) Toxoplasmosis (5)
Vitamin D (OHD) Vitamin D (OHD)
Total/normalized calcium Total/normalized calcium
Selenium (5) Selenium (5)
Thyroxine (T4) Thyroxine (T4)
Thyroid-stimulating hormone Thyroid-stimulating hormone
Antithyroglobulin antibodies Antithyroglobulin antibodies
Antimicrosomal antibodies Antimicrosomal antibodies
FSH/LH (females aged 35-60 years)
Insulin (6)
C-peptide (6)
Biochemistry profile (5) Biochemistry profile (5)
Bicarbonate Bicarbonate
Blood urea nitrogen Blood urea nitrogen
Total bilirubin Total bilirubin
Alkaline phosphatase Alkaline phosphatase
Cholesterol Cholesterol
AST AST
ALT ALT
LDH LDH
GGT GGT
Total protein Total protein
Albumin Albumin
Creatinine Creatinine
Glucose Glucose
Calcium Calcium
Chloride Chloride
Uric acid Uric acid
Phosphorus Phosphorus
Sodium Sodium
Potassium Potassium
Triglycerides Triglycerides
Globulin Globulin
Iron Iron
Osmolality Osmolality
Appendix 1. Blood and Urine Assessments by Specimen Type and Age Group
(continued)
AGE GROUP
12-19 years 20 years and older
Plasma
Glucose (examinees aged 20-39
years and 75 years and older)
OGTT (examinees aged 40-74
years)
Fibrinogen (examinees aged 40
years and older)(5)
Urine
Cadmium Cadmium
Creatinine Creatinine
Albumin Albumin
Iodine Iodine
Urine drug (ages 18 Urine drug (examinees aged 18
years and over)(2)(3) years and over)(2)(3)
Cocaine Cocaine
Opiates Opiates
Phencyclidine Phencyclidine
Amphetamines Amphetamines
Marijuana Marijuana
Pregnancy test (females aged
20-59 years)
White Cells
Storage/banking (5) Storage/banking (5)
(1) Includes hematocrit, hemoglobin, red, white and platelet cell counts,
mean cell volume, mean cell hemoglobin, mean cell hemoglobin concentration,
red cell distribution width, platelet distribution width, mean platelet
volume, and 3-cell differential
(2) Phase 2 only
(3) Anonymous
(4) Phase 1 only
(5) Home examination also
(6) In phase 2, also from second venipuncture for examinees aged 40-74 years
Appendix 2. Laboratory Test Detection Limits
Test Detection limit
Albumin (urine) 0.5 ug/mL
Alpha carotene 0 ug/dL
Antimicrosomal antibody (AMA) 0.5 U/mL
Antithyroglobulin antibody (ATA) 1.0 U/mL
Beta carotene 0.67 ug/dL
Beta cryptoxanthin 0 ug/dL
C-peptide 0.03 pmol/mL
C-reactive protein 0.3 mg/dL
Cadmium (urine) 0.01 ng/mL
Cotinine 0.05 ng/mL
Creatinine (urine) 1 mg/dL
Erythrocyte protoporphyrin 2.5 ug/dL RBC
Ferritin 3 ng/mL
Folate (serum) 0.2 ng/mL
Follicle stimulating hormone (FSH) 0.15 IU/L
Glucose 2 mg/dL
Glycated hemoglobin 0 %
Hematology parameters
Granulocyte 0 %
Granulocyte (1) 0 number
Hematocrit 0 %
Hemoglobin 0 g/dL
Lymphocyte 0 %
Lymphocyte (1) 0 number
Mean cell hemoglobin 0 pg
Mean cell hemoglobin
concentration 0 g/dL
Monocyte 0 %
Monocyte (1) 0 number
Platelet count (1) 0
Platelet distribution width 0 %
Red blood cell count (RBC) (1) 0
Red blood cell distribution width 0 %
White blood cell count (WBC) (1) 0
Hepatitis profile Qualitative tests
Herpes Qualitative tests
High density lipoprotein (HDL) 10 mg/dL
Human immunodeficiency virus (HIV) Qualitative tests
Insulin 2.5 uU/mL
Iodine (urine) 0.2 ug/dL
Iron 3.0 ug/dL
Lead 1 ug/dL
Lipoprotein(a) 0 mg/dL
Lutein/zeaxanthin 0.43 ug/dL
Appendix 2. Laboratory Test Detection Limits (continued)
Test Detection limit
Luteinizing hormone (LH) 0.15 IU/L
Lycopene 0.63 ug/dL
Normalized calcium 0.5 mmol/L
RBC folate 4.4 ng/mL
Retinyl esters 0 ug/dL
Rheumatoid factor Qualitative tests
Rubella 0 IU
Selenium 8 ng/mL
Tetanus 0 U/mL
Thyroid stimulating hormone (TSH) 0.01 mU/mL
Thyroxine (T4) 1.0 ug/dL
Total iron binding capacity (TIBC) 9 ug/dL
Total cholesterol 10 mg/dL
Total calcium 1.5 mmol/L
Toxoplasmosis 0 IU
Triglycerides 10 mg/dL
Varicella 0
Vitamin B12 20 pg/mL
Vitamin E 20 ug/dL
Vitamin C 0 mg/dL
Vitamin A 0.5 ug/dL
Vitamin D 5.0 ng/mL
(1) Units for white blood cell count, red blood cell count, platelet
count, lymphocyte number, granulocyte number, and mononuclear number are
referenced in the Manual for Medical Technicians p. 5-1 (U.S. DHHS, 1996).
Note: Lower detection limits for analytes included in the general
"biochemistry profile" are found in the Laboratory Procedures Used for
NHANES III (U.S. DHHS, 1996).
Appendix 3. NHANES III SI Table
NHANES NHANES Conversion SI SI
Test (1) Unit Format Factor Unit Format
Alanine
aminotransferase(2) N/A N/A N/A U/L XXX
Albumin (serum) (2) g/dL X.X 10 g/L XX
Albumin (urine) ug/mL XXXXX.XX N/A N/A N/A
Alkaline
phosphatase (2) N/A N/A N/A U/L XXX
Alpha carotene ug/dL XXX 0.01863 umol/L X.XX
Antimicrosomal
antibody N/A N/A N/A N/A N/A
Antithyroglobulin
antibody N/A N/A N/A N/A N/A
Apolipoprotein AI mg/dL XXX 0.01 g/L X.XX
Apolipoprotein B mg/dL XXX 0.01 g/L X.XX
Aspartate amino-
transferase (2) N/A N/A N/A U/L XXX
Beta carotene ug/dL XXX 0.01863 umol/L XX.XX
Beta cryptoxanthin ug/dL XXX 0.01809 umol/L X.XX
Bicarbonate (2) N/A N/A N/A mmol/L XX
Bilirubin (total)(2) mg/dL XX.X 17.1 umol/L XXX.XX
Blood urea
nitrogen (2) mg/dL XXX 0.357 mmol/L XX.XX
C-peptide pmol/mL XX.XXX 1 nmol/L XX.XXX
C-reactive protein N/A N/A N/A N/A N/A
Cadmium (urine) ng/mL XX.XX 8.897 nmol/L XXX.XX
Calcium (total) N/A N/A N/A mmol/L X.XX
Calcium (normalized) N/A N/A N/A mmol/L X.XX
Calcium (2) mg/dL XX.X 0.25 mmol/L X.XXX
Chloride (2) N/A N/A N/A mmol/L XXX.X
Cholesterol mg/dL XXX 0.02586 mmol/L XX.XX
Cholesterol (HDL) mg/dL XXX 0.02586 mmol/L X.XX
Cholesterol (LDL) mg/dL XXX 0.02586 mmol/L X.XX
Cholesterol (2) mg/dL XXX 0.02586 mmol/L XX.XXX
Cotinine ng/mL XXXX.XXX N/A N/A N/A
Creatinine (2) mg/dL XX.X 88.4 umol/L XXXX.X
Creatinine (urine) mg/dL XXX.X 0.0884 mmol/L XX.X
Diphtheria N/A N/A N/A N/A N/A
Ferritin ng/mL XXXX 1 ug/L XXXX
Fibrinogen mg/dL XXX 0.01 g/L X.XX
Folate ng/mL XXX.X 2.266 nmol/L XXX.X
Folate (RBC) ng/mL XXXX 2.266 nmol/L XXXX.X
Follicle-stimulating
hormone N/A N/A N/A IU/L XXX.X
GGT (2) N/A N/A N/A U/L XXXX
Appendix 3. NHANES III SI Table
NHANES NHANES Conversion SI SI
Test (1) Unit Format Factor Unit Format
Globulin (2) g/dL X.X 10 g/L XX
Glucose (2) mg/dL XXX 0.05551 mmol/L XX.XX
Glucose (plasma) mg/dL XXX.X 0.05551 mmol/L XX.XXX
Glycated
hemoglobin % XX.X N/A N/A N/A
Helicobacter pylori N/A N/A N/A N/A N/A
Hematocrit % XX.XX 0.01 L/L=1 0.XXX
Hemoglobin g/dL XX.XX 10 g/L XXX.X
Hepatitis A virus N/A N/A N/A N/A N/A
Hepatitis B core
antibody (anti-HBc) N/A N/A N/A N/A N/A
Hepatitis B surface
antigen (HbsAg) N/A N/A N/A N/A N/A
Hepatitis C virus N/A N/A N/A N/A N/A
Hepatitis D virus N/A N/A N/A N/A N/A
Hepatitis B surface
antibody (anti-HBs) N/A N/A N/A N/A N/A
Herpes I & II N/A N/A N/A N/A N/A
Homocysteine N/A N/A N/A umol/L XX.X
Human immuno-
deficiency virus N/A N/A N/A N/A N/A
Insulin uU/mL XXX.XX 6.0 pmol/L XXX.XX
Iodine (urine) ug/dL XXX.X N/A N/A N/A
Iron ug/dL XXX 0.1791 umol/L XX.XX
Iron (2) ug/dL XXX 0.1791 umol/L XX.X
LDH (2) N/A N/A N/A U/L XXX
Latex antibody IU/mL XXXX.XX N/A N/A N/A
Lead ug/dL XX.X 0.04826 umol/L X.XXX
Lipoprotein(a) mg/dL XXX 0.01 g/L X.XX
Lutein/zeaxanthin ug/dL XXX 0.01758 umol/L X.XX
Luteinizing hormone N/A N/A N/A IU/L XX.X
Lycopene ug/dL XXX 0.01863 umol/L X.XX
Mean cell
hemoglobin N/A N/A N/A pg XX.XX
Mean cell
volume N/A N/A N/A fL XXX.XX
Mean cell
hemoglobin
concentration g/dL XX.XX 10 g/L XXX.X
Mean platelet
volume N/A N/A N/A fL XX.XX
Methylmalonic acid ug/dL N/A 0.085 umol/L N/A
Appendix 3. NHANES III SI Table (continued)
NHANES NHANES Conversion SI SI
Test (1) Unit Format Factor Unit Format
Osmolality (2) N/A N/A N/A mmol/kg XXX
Phosphorus (2) mg/dL XX.X 0.3229 mmol/L X.XXX
Platelet count (3) N/A XXX.X 1 N/A XXX.X
Potassium (2) N/A N/A N/A mmol/L X.XX
Protein (total)(2) g/dL XX.X 10 g/L XXX
Protoporphyrin ug/dL XXXX 0.0178 umol/L XX.XX
Red blood cell
distribution width % XX.XX 0.01 fraction X.XXXX
Red blood cell
count (3) N/A X.XX 1 N/A X.XX
Retinyl esters ug/dL XXX 0.03491 umol/L X.XX
Rheumatoid factor N/A N/A N/A N/A N/A
Rubella N/A N/A N/A N/A N/A
Selenium ng/mL XXX 0.0127 nmol/L X.XX
Sodium (2) N/A N/A N/A mmol/L XXX.X
Tetanus U/mL N/A N/A N/A N/A
Thyroid stimulating
hormone uU/mL XXX.XX 1 mU/L XXX.XX
Thyroxine ug/dL XX.X 12.87 nmol/L XXX.X
Total iron binding
capacity ug/dL XXX 0.1791 umol/L XXX.XX
Toxoplasmosis N/A N/A N/A N/A N/A
Triglycerides mg/dL XXXX 0.01129 mmol/L XX.XX
Triglycerides (2) mg/dL XXXX 0.01129 mmol/L XX.XXX
Uric acid (2) mg/dL XX.X 59.48 umol/L XXX.X
Varicella N/A N/A N/A N/A N/A
Vitamin A ug/dL XXX 0.03491 umol/L X.XX
Vitamin B12 pg/mL XXXXX 0.7378 pmol/L XXXXX.XX
Vitamin C mg/dL X.XX 56.78 mmol/L XXX.XX
Vitamin D ng/mL XXX.X 2.496 nmol/L XXX.X
Vitamin E ug/dL XXXX 0.02322 umol/L XXX.XX
White blood cell
count (3) N/A XX.XX 1 N/A XX.XX
(1) Results are based on a serum sample unless otherwise noted.
(2) Biochemistry profile
(3) Units for white blood cell count, red blood cell count, platelet
count, lymphocyte number, granulocyte number, and mononuclear number are
referenced in the Manual for Medical Technicians p. 5-1 (U.S. DHHS, 1996).
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